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Medications for Sinus Symptoms

Sinus symptoms are associated with a variety of upper respiratory tract disorders including the common cold, sinus infection, hay fever and are characterized by congestion of the nasal mucous membrane, watery nasal rhinorrhea, facial pain especially around eyes, nose & forehead, earache, dental pain, sneezing, fever and bad breath.

Drugs used to treat Sinus Symptoms

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Advil Cold and Sinus 7.5 30 reviews for Advil Cold and Sinus to treat Sinus Symptoms
OTC C N X
Generic name:
ibuprofen / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mometasone 2.9 48 reviews for mometasone to treat Sinus Symptoms
Rx/OTC C N
Generic name:
mometasone nasal
Brand names:
Nasonex 24HR Allergy, Propel
Drug class:
nasal steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sudafed PE Sinus Pressure + Pain 4.0 1 review for Sudafed PE Sinus Pressure + Pain to treat Sinus Symptoms
OTC N N X
Generic name:
acetaminophen / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
guaifenesin / phenylephrine 9.2 11 reviews for guaifenesin / phenylephrine to treat Sinus Symptoms
Rx/OTC C N
Generic name:
guaifenesin / phenylephrine systemic
Brand names:
Mucus Relief Sinus, Deconex, Gilphex TR, Deconex IR, Aldex G, Aquatab D, D-Phen 1000, Despec, Donatussin Drops, Duravent PE, ED Bron GP, Nariz, Prolex D, Rescon-GG, Supress-PE, Xpect-PE, Zotex-GP
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
ibuprofen / pseudoephedrine 7.7 35 reviews for ibuprofen / pseudoephedrine to treat Sinus Symptoms
OTC C N X
Generic name:
ibuprofen / pseudoephedrine systemic
Brand names:
Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gels, Motrin Childrens Cold
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Aleve-D Sinus & Cold 9.5 2 reviews for Aleve-D Sinus & Cold to treat Sinus Symptoms
OTC N N X
Generic name:
naproxen / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Tylenol Sinus + Headache Day Rate Add review
OTC N N X
Generic name:
acetaminophen / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
acetaminophen / chlorpheniramine / phenylephrine 8.0 4 reviews for acetaminophen / chlorpheniramine / phenylephrine to treat Sinus Symptoms
Rx/OTC N N X
Generic name:
acetaminophen / chlorpheniramine / phenylephrine systemic
Brand names:
Allergy Multi-Symptom, Norel AD, Tylenol Allergy Multi-Symptom, Tylenol Sinus Congestion & Pain Nighttime, Dristan Cold Multi Symptom Formula, Comtrex Severe Cold & Sinus, Robitussin Peak Cold Nighttime Nasal Relief, Comtrex Flu Therapy, Contac Cold + Flu (Night Formula), GNP Cold Relief Plus, Medicidin-D, Onset Forte, Relief-PE, Tylenol Plus Children's Cold
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Nasonex 24HR Allergy Rate Add review
OTC C N
Generic name:
mometasone nasal
Drug class:
nasal steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Allergy Multi-Symptom Rate Add review
Rx/OTC N N X
Generic name:
acetaminophen / chlorpheniramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Vicks Dayquil Cold & Flu Relief 10 1 review for Vicks Dayquil Cold & Flu Relief to treat Sinus Symptoms
OTC N N X
Generic name:
acetaminophen / dextromethorphan / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
acetaminophen / phenylephrine 8.0 6 reviews for acetaminophen / phenylephrine to treat Sinus Symptoms
OTC N N X
Generic name:
acetaminophen / phenylephrine systemic
Brand names:
Sudafed PE Sinus Pressure + Pain, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Excedrin Sinus Headache, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Contac Cold + Flu (Day Formula), Mapap Sinus Congestion and Pain
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
acetaminophen / pseudoephedrine 9.4 9 reviews for acetaminophen / pseudoephedrine to treat Sinus Symptoms
OTC N N X
Generic name:
acetaminophen / pseudoephedrine systemic
Brand names:
Allerest No Drowsiness, Ornex, Dristan Cold Non-Drowsy, Nexafed Sinus Pressure + Pain
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Advil Cold and Sinus Liqui-Gels 10 2 reviews for Advil Cold and Sinus Liqui-Gels to treat Sinus Symptoms
OTC C N X
Generic name:
ibuprofen / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Norel AD 2.0 1 review for Norel AD to treat Sinus Symptoms
Rx/OTC N N X
Generic name:
acetaminophen / chlorpheniramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
dexbrompheniramine / pseudoephedrine 10 12 reviews for dexbrompheniramine / pseudoephedrine to treat Sinus Symptoms
Rx/OTC C N X
Generic name:
dexbrompheniramine / pseudoephedrine systemic
Brand names:
Drixoral Cold and Allergy, Conex, Dixaphedrine
Drug class:
upper respiratory combinations
For consumers:
interactions, side effects
Propel Rate Add review
Rx C N
Generic name:
mometasone nasal
Drug class:
nasal steroids
For consumers:
dosage, interactions, side effects
Sudafed 12 Hour Pressure+Pain Rate Add review
OTC N N X
Generic name:
naproxen / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Mucus Relief Sinus 10 1 review for Mucus Relief Sinus to treat Sinus Symptoms
Rx/OTC C N
Generic name:
guaifenesin / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
naproxen / pseudoephedrine 9.7 3 reviews for naproxen / pseudoephedrine to treat Sinus Symptoms
OTC N N X
Generic name:
naproxen / pseudoephedrine systemic
Brand names:
Aleve-D Sinus & Cold, Sudafed 12 Hour Pressure+Pain, Aleve-D Sinus & Headache
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Tylenol Allergy Multi-Symptom Rate Add review
Rx/OTC N N X
Generic name:
acetaminophen / chlorpheniramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Vicks Sinex Daytime Rate Add review
OTC N N X
Generic name:
acetaminophen / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
acetaminophen / dextromethorphan / phenylephrine 9.0 2 reviews for acetaminophen / dextromethorphan / phenylephrine to treat Sinus Symptoms
OTC N N X
Generic name:
acetaminophen / dextromethorphan / phenylephrine systemic
Brand names:
Vicks Dayquil Cold & Flu Relief, Robitussin Peak Cold Daytime Cold + Flu, Sudafed PE Pressure+Pain+Cough, Theraflu Daytime Severe Cold & Cough, Theraflu Warming Relief Daytime Severe Cold & Cough, Tylenol Cold Max Day, Comtrex Cold and Cough Maximum Strength
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Deconex Rate Add review
Rx/OTC C N
Generic name:
guaifenesin / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Excedrin Sinus Headache Rate Add review
OTC N N X
Generic name:
acetaminophen / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects

Frequently asked questions

Alternative treatments for Sinus Symptoms

The following products are considered to be alternative treatments or natural remedies for Sinus Symptoms. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Sinus Symptoms.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.