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Ergonovine Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 13, 2023.

Applies to ergonovine: compounding powder, injectable solution, oral tablet.

General

Administration of correct dose to carefully selected patients who are closely monitored, yields little risk of serious adverse systemic effects; however, IV administration may produce serious adverse effects if the injections are not diluted and administered slowly.[Ref]

Cardiovascular

Frequency not reported: Gangrene, coronary artery vasospasm, peripheral vasospasm, hypotension, hypertension, thrombophlebitis, myocardial infarction (single case report), ventricular arrhythmias, transient chest pain, palpitation, bradycardia, vasoconstriction

Gastrointestinal

Very rare (less than 0.01%): Mesenteric ischemia and large bowel infarction (single case report)

Frequency not reported: Abdominal pain, diarrhea, nausea, esophageal spasm, vomiting, unpleasant taste

Hypersensitivity

Frequency not reported: Allergic phenomena (including shock, hypertension, chest pain, palpitation, dyspnea, and bradycardia), anaphylactic/anaphylactoid reaction

Nervous system

Frequency not reported: Dizziness, headache

Metabolic

Frequency not reported: Clinical exacerbations of porphyria, water intoxication

Dermatologic

Frequency not reported: Sweating, diaphoresis, skin rashes

Respiratory

Frequency not reported: Dyspnea, nasal congestion, pulmonary edema, pleural thickening

Musculoskeletal

Very rare (less than 0.01%): Unmasking of myasthenia gravis (single case report)

Frequency not reported: Leg cramps

Postmarketing reports: Muscle spasm

Ocular

Postmarketing reports: Eye movement disorder

Psychiatric

Frequency not reported: Hallucinations

Genitourinary

Frequency not reported: Hematuria

Hepatic

Frequency not reported: Abnormal liver function test

Other

Frequency not reported: Vertigo, tinnitus

Renal

Postmarketing reports: Increased blood creatine

References

1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Cerner Multum, Inc. Canadian Product Information. 2015.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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