Entereg Side Effects
Generic Name: alvimopan
Note: This page contains information about the side effects of alvimopan. Some of the dosage forms included on this document may not apply to the brand name Entereg.
More frequent side effects include constipation. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to alvimopan: oral capsule
In addition to its needed effects, some unwanted effects may be caused by alvimopan (the active ingredient contained in Entereg). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking alvimopan:More common
- Acid or sour stomach
- decreased urine
- difficulty having a bowel movement (stool)
- dry mouth
- excess air or gas in stomach or intestines
- full feeling
- increased thirst
- irregular heartbeat
- loss of appetite
- mood changes
- muscle pain or cramps
- nausea or vomiting
- numbness or tingling in hands, feet, or lips
- pale skin
- passing gas
- shortness of breath
- stomach discomfort, upset, or pain
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
- Decrease in frequency of urination
- decrease in urine volume
- difficulty in passing urine (dribbling)
- painful urination
Some of the side effects that can occur with alvimopan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common
- Back pain
For Healthcare Professionals
Applies to alvimopan: oral capsule
Hematologic side effects including anemia (5.2% to 5.4%).[Ref]
Genitourinary side effects have included urinary retention (3.2% to 3.5%).[Ref]
Gastrointestinal side effects have included constipation (4% to 9.7%), flatulence (3.1% to 8.7%), and dyspepsia (5.9% to 7%).[Ref]
Metabolic side effects have included hypokalemia (6.9% to 9.5%).[Ref]
Musculoskeletal side effects have included back pain (3.3% to 3.4%).[Ref]
1. "Product Information. Entereg (alvimopan)." GlaxoSmithKline, Research Triangle Park, NC.
Not all side effects for Entereg may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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