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Dexamethasone / tobramycin ophthalmic Side Effects

Not all side effects for dexamethasone / tobramycin ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to dexamethasone / tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension

In addition to its needed effects, some unwanted effects may be caused by dexamethasone / tobramycin ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking dexamethasone / tobramycin ophthalmic, check with your doctor or nurse as soon as possible:

Less common
  • Itching and swelling of eyelid
  • redness of eye
  • Delayed wound healing
  • eye pain
  • gradual blurring or loss of vision

For Healthcare Professionals

Applies to dexamethasone / tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension


Hypersensitivity reactions have been reported with dexamethasone-tobramycin.[Ref]


Ocular side effects have included lid itching, swelling, and conjunctival hyperemia in < 4% of patients. The dexamethasone component has been associated with elevation of intraocular pressure with possible development of glaucoma, delayed wound healing, posterior subcapsular cataract formation, and optic nerve damage.

Corticosteroid containing preparations have also been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis.[Ref]


The development of a secondary infection has been reported in patients treated with antimicrobial and corticosteroid combinations. Fungal and viral infections of the cornea can develop with long-term application of corticosteroids.[Ref]


1. "Product Information. Tobradex (dexamethasone-tobramycin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

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