Calfactant Side Effects

Not all side effects for calfactant may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to calfactant: intratracheal suspension

Calfactant causes few side effects. There is a possibility that the baby will have breathing difficulties during the calfactant treatment, and these problems may require further treatment by health care professionals. Your baby will remain under constant supervision during treatment with calfactant.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to calfactant: intratracheal suspension

Cardiovascular

Cardiovascular side effects have included cyanosis (65%) and bradycardia (34%).

Respiratory

Respiratory side effects have included airway obstruction (39%), requirement for manual ventilation (16%), and reintubation (3%).

Other

Other side effects have included reflux of surfactant into endotracheal tube (21%), intraventricular hemorrhage (IVH), and periventricular leukomalacia (PVL). The IVH and PVL were not associated with increased mortality.

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