Erythromycin Pregnancy and Breast Feeding Warnings
Erythromycin is also known as: E-Mycin, E.E.S. Granules, E.E.S.-200, E.E.S.-400, E.E.S.-400 Filmtab, Ery-Tab, Eryc, EryPed, Erythrocin, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, Erythrocot, Ilosone, PCE Dispertab, Robimycin
Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using E. E. S. Suspension while you are pregnant. E. E. S. Suspension is found in breast milk. If you are or will be breast-feeding while you use E. E. S. Suspension, check with your doctor. Discuss any possible risks to your baby.
Erythromycin Pregnancy Warnings
Erythromycin has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. The Centers for Disease Control and Prevention considers erythromycin the drug of choice for treatment of Chlamydia infections in pregnant women. However, erythromycin estolate is considered contraindicated because of drug-related hepatotoxicity. Erythromycin should only be given during pregnancy when need has been clearly established.
Erythromycin crosses the placenta in small amounts. In one study of 11 patients who had detectable erythromycin levels in the serum, 4 infants did not have detectable cord concentrations. The cord concentrations in the remaining 7 infants generally ranged from 1% to 6% of that found in maternal serum. A case of left absence-of-tibia syndrome was reported in an infant whose mother had received erythromycin, ethisterone, and ethinyl estradiol at approximately 4 weeks gestation. Erythromycin has been used prior to delivery in women colonized with group B beta-hemolytic streptococcus to reduce infant colonization. No adverse events in the infants have been reported. Erythromycin has also been used to treat genital Mycoplasma infection during the first trimester without evidence of fetal adverse effects. Pregnant women receiving erythromycin estolate may be more prone to hepatotoxicity. In one study of women receiving erythromycin estolate between the 22nd and 32nd week of pregnancy, 10% showed abnormal levels of SGOT.
Erythromycin Lactation Warnings
Erythromycin is excreted into human milk in small amounts. Erythromycin is considered compatible with breast-feeding by the American Academy of Pediatrics.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
