Olopatadine Hydrochloride
Pronouncation: (oh-low-pat-AD-een HIGH-droe-KLOR-ide)Class: Ophthalmic antihistamine
Trade Names:
Patanol
- Solution 0.1%
Pharmacology
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Inhibits release of histamine from mast cells and relatively selective histamine H1 antagonist. Inhibits type 1 immediate hypersensitivity reactions.
Indications and Usage
Temporary relief of itching caused by allergic conjunctivitis.
Contraindications
Standard considerations.
Dosage and Administration
Adults and Children1 to 2 drops in affected eye(s) twice daily, 6 to 8 h apart. If using other topical ophthalmic drugs, separate each medication by 5 min or more.
Storage/Stability
Store between 39° and 86°F. Keep bottle tightly closed.
Drug Interactions
None well documented.
Laboratory Test Interactions
None well documented.
Adverse Reactions
Ophthalmic
Burning, dry eye, foreign body sensation, hyperemia, keratitis, lid edema, pruritus, stinging.
Miscellaneous
Asthenia, cold syndrome, dysgeusia, headache, pharyngitis, rhinitis, sinusitis.
Precautions
Pregnancy
Category C .
Lactation
Secreted into animal breast milk.
Children
Safety and effectiveness younger than 3 yr of age are not established. Do not instill while wearing contact lenses.
Patient Information
- Advise patient that usual dose is 1 drop in affected eye(s) twice daily at an interval of 6 to 8 h.
- Teach patient proper technique for instilling eye drops: Wash hands; do not allow dropper to touch eye; tilt head back, look up; pull lower eyelid down; instill prescribed number of drops; close eye for 1 to 2 min and apply gentle pressure to bridge of nose; do not rub eye.
- Advise patients who wear contact lenses to remove their lenses before instilling this medicine and to wait at least 10 min after instilling eye drop before inserting their lenses. Also, caution these patients to not wear their lenses if the eye is red.
- Advise patient that if more than 1 topical ophthalmic drug is being used, administer the drugs at least 5 min apart.
- Advise patient to inform health care provider if experiencing side effects or if eye symptoms do not improve or worsen.
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Seasonal Allergic Conjunctivitis










