Pred-G (ophthalmic)

Generic name: gentamicin and prednisolone (ophthalmic) [ JEN-ta-MYE-sin-and-pred-NIS-oh-lone-off-THAL-mik ]
Brand names: Pred-G, Pred-G S.O.P. ophthalmic
Drug class: Ophthalmic steroids with anti-infectives

Medically reviewed by Drugs.com on Aug 4, 2023. Written by Cerner Multum.

What is Pred-G?

Pred-G (for the eyes) is a combination antibiotic and steroid medicine that is used to treat eye inflammation caused by uveitis, eye injury, radiation, chemical burns, or certain other conditions.

Pred-G is used when there is a risk of bacterial infection in or around the eye.

Pred-G may also be used for purposes not listed in this medication guide.

Pred-G side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Serious side effects are unlikely when Pred-G is used in the eyes, but can occur if the medicine is absorbed into your bloodstream.

Pred-G may cause serious side effects. Call your doctor at once if you have:

• eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);

• eye pain, tearing, sensitivity to light;

• blurred vision, tunnel vision, seeing halos around lights; or

• a wound that will not heal.

Stop using this medicine and talk to your doctor if you have new or worsening eye pain or swelling that lasts longer than 48 hours.

Common side effects of Pred-G may include:

• burning, stinging, redness, or other irritation of the eyes;

• blurred vision;

• feeling like something is in your eye; or

• unusual or unpleasant taste in the mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

prednisone, diclofenac ophthalmic, ciprofloxacin ophthalmic, azithromycin ophthalmic, triamcinolone ophthalmic, triamcinolone, dexamethasone ophthalmic

Warnings

You should not use Pred-G if you have a fungal or viral infection in your eyes (including herpes simplex).

Before taking this medicine

You should not use this medicine if you are allergic to gentamicin or prednisolone, or if you have a fungal or viral infection in your eyes (including herpes simplex).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

You should not breast-feed while using this medicine.

This medicine is not approved for use by anyone younger than 18 years old.

How should I use Pred-G?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using eye medication.

Shake the eye drops well just before each use.

To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the number of drops your doctor has prescribed.

Do not the eye drops use while wearing soft contact lenses. A preservative in Pred-G could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses.

To apply the ointment: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Squeeze a ribbon of ointment from the tube into this pocket. Blink your eye gently and then keep it closed for 1 or 2 minutes. Wipe excess ointment from your eyelashes using a clean tissue.

Do not touch the tip of the dropper or tube, or place it directly on your eye. A contaminated tip can infect your eye, which could lead to serious vision problems.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

An overdose of Pred-G ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using gentamicin and prednisolone?

Do not share Pred-G with another person, even if they have the same symptoms you have.

Avoid driving or doing anything that requires you to be able to see clearly. You may have blurred vision for a short time.

Do not use other eye medications unless your doctor tells you to.

What other drugs will affect Pred-G?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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