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Hydroxypropyl Cellulose

Excipient (pharmacologically inactive substance)

What is Hydroxypropyl Cellulose?

Hydroxypropyl cellulose, also commonly known as hydroxypropyl methycellulose (HPMC) or hypromellose is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry. It has also been used as a rate-controlling polymer for sustained-release dose forms.[1]

As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes. In the US, it is available over-the-counter (OTC) in such products as Isopto-Tears and Nature’s Tears.[2]

[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011

[2] Innovate Us. What is Hypromellose? http://www.innovateus.net/health/what-hypromellose. Accessed 08/19/2011

Top Medications Containing Hydroxypropyl Cellulose