Vandetanib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with vandetanib.
Moderate
Vandetanib High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
vandetanib - hypertension
Hypertension, including hypertensive crisis, has occurred in patients treated with vandetanib. Monitor all patients for hypertension and a dose reduction or interruption may be necessary. If hypertension cannot be controlled, do not resume vandetanib. Care should be taken when using this agent in hypertensive patients. Close monitoring is recommended.
References
- (2011) "Product Information. Vandetanib (vandetanib)." Astra-Zeneca Pharmaceuticals
Vandetanib drug interactions
There are 313 drug interactions with vandetanib.
Vandetanib disease interactions
There are 10 disease interactions with vandetanib which include:
- QT prolongation
- lung toxicity
- heart failure
- hemorrhage
- hepatic impairment
- hypertension
- hypothyroidism
- ischemic attack
- renal impairment
- RPL syndrome
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
