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Uptravi and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Uptravi (selexipag).

Minor

Selexipag Food

Minor Food Interaction

Food prolongs the gastrointestinal absorption of selexipag. When taken with food, the time to peak concentration (Tmax) was delayed and peak plasma concentration (Cmax) was approximately 30% lower. Selexipag systemic exposure (AUC) and that of its active metabolite did not significantly change, however. Selexipag may be taken with or without food. Tolerability may be improved when taken with food.

References

  1. (2016) "Product Information. Uptravi (selexipag)." Actelion Pharmaceuticals US Inc

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Uptravi drug interactions

There are 230 drug interactions with Uptravi (selexipag).

Uptravi disease interactions

There are 2 disease interactions with Uptravi (selexipag) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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