Uptravi FDA Approval History
Last updated by Judith Stewart, BPharm on Aug 6, 2021.
FDA Approved: Yes (First approved December 21, 2015)
Brand name: Uptravi
Generic name: selexipag
Dosage form: Tablets and Lyophilized Powder for Injection
Company: Actelion Pharmaceuticals US, Inc.
Treatment for: Pulmonary Arterial Hypertension
Uptravi (selexipag) is a prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension (PAH).
- Uptravi is indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) to delay disease progression and reduce the risk of hospitalization for PAH.
- Uptravi is administered orally (Uptravi tablets) or by intravenous infusion (Uptravi IV) twice daily.
- Uptravi IV is used in patients who are temporarily unable to take oral therapy.
- Common adverse reactions include headache, diarrhea, jaw pain, nausea, myalgia, vomiting, pain in extremity, and flushing.
Development timeline for Uptravi
Further information
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