Antinaus 50 and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Antinaus 50 (promethazine).
promethazine Alcohol (Ethanol)
Moderate Drug Interaction
GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.
MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.
References
- Lutz EG "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA 236 (1976): 2422-3
- Freed E "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust 2 (1981): 44-5
Antinaus 50 drug interactions
There are 685 drug interactions with Antinaus 50 (promethazine).
Antinaus 50 disease interactions
There are 18 disease interactions with Antinaus 50 (promethazine) which include:
- acute alcohol intoxication
- cardiovascular disease
- CNS depression
- head injury
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- dystonic reactions
- hematologic toxicity
- liver disease
- NMS
- parkinsonism
- renal dysfunction
- seizure disorders
- tardive dyskinesia
- antidopaminergic effects 2
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More about Antinaus 50 (promethazine)
- Antinaus 50 consumer information
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- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.