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Xenical and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Xenical (orlistat).

Moderate

multivitamins with minerals orlistat

Moderate Drug Interaction

ADJUST DOSING INTERVAL: Orlistat decreases the absorption of fat-soluble vitamins. Studies have shown a 30% reduction in beta-carotene absorption and a 60% reduction in tocopherol acetate absorption when coadministered with orlistat.

MANAGEMENT: Vitamin supplements should be taken at least two hours before or after orlistat administration.

References

  1. "Product Information. Xenical (orlistat)." Roche Laboratories PROD (2001):

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Xenical drug interactions

There are 142 drug interactions with Xenical (orlistat).

Xenical disease interactions

There are 4 disease interactions with Xenical (orlistat) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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