Benicar HCT (hydrochlorothiazide / olmesartan) and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with Benicar HCT (hydrochlorothiazide / olmesartan) which include:
hydrochlorothiazide ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Hydrochlorothiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
olmesartan ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Moderate-to-high dietary intake of potassium, especially salt substitutes, may increase the risk of hyperkalemia in some patients who are using angiotensin II receptor blockers (ARBs). ARBs can promote hyperkalemia through inhibition of angiotensin II-induced aldosterone secretion. Patients with diabetes, heart failure, dehydration, or renal insufficiency have a greater risk of developing hyperkalemia.
MANAGEMENT: Patients should receive dietary counseling and be advised to not use potassium-containing salt substitutes or over-the-counter potassium supplements without consulting their physician. If salt substitutes are used concurrently, regular monitoring of serum potassium levels is recommended. Patients should also be advised to seek medical attention if they experience symptoms of hyperkalemia such as weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.
- "Product Information. Cozaar (losartan)." Merck & Co, Inc, West Point, PA.
- "Product Information. Diovan (valsartan)." Novartis Pharmaceuticals, East Hanover, NJ.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
thiazides - hyperlipidemia
Thiazide diuretics may increase serum triglyceride and cholesterol levels, primarily LDL and VLDL. Whether these effects are dose-related and sustained during chronic therapy are unknown. Patients with preexisting hyperlipidemia may require closer monitoring during thiazide therapy, and adjustments made accordingly in their lipid-lowering regimen
- Ames RP "A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides." Am J Cardiol 77 (1996): b12-6
- Slotkoff L "Clinical efficacy and safety of indapamide in the treatment of edema." Am Heart J 106 (1983): 233-7
- Freis ED "The efficacy and safety of diuretics in treating hypertension." Ann Intern Med 122 (1995): 223-6
You should also know about...
Benicar HCT (hydrochlorothiazide / olmesartan) drug Interactions
There are 783 drug interactions with Benicar HCT (hydrochlorothiazide / olmesartan)
Benicar HCT (hydrochlorothiazide / olmesartan) disease Interactions
There are 14 disease interactions with Benicar HCT (hydrochlorothiazide / olmesartan) which include:
- Electrolyte Losses
- Liver Disease
- Lupus Erythematosus
- Renal Function Disorders
- Renal Artery Stenosis
- Renal/Liver Disease
- Thyroid Function Tests
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Do not stop taking any medications without consulting your healthcare provider.