Avalide (hydrochlorothiazide / irbesartan) and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with Avalide (hydrochlorothiazide / irbesartan) which include:
hydrochlorothiazide ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Hydrochlorothiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
irbesartan ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Moderate-to-high dietary intake of potassium, especially salt substitutes, may increase the risk of hyperkalemia in some patients who are using angiotensin II receptor blockers (ARBs). ARBs can promote hyperkalemia through inhibition of angiotensin II-induced aldosterone secretion. Patients with diabetes, heart failure, dehydration, or renal insufficiency have a greater risk of developing hyperkalemia.
MANAGEMENT: Patients should receive dietary counseling and be advised to not use potassium-containing salt substitutes or over-the-counter potassium supplements without consulting their physician. If salt substitutes are used concurrently, regular monitoring of serum potassium levels is recommended. Patients should also be advised to seek medical attention if they experience symptoms of hyperkalemia such as weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
thiazides - hyperlipidemia
Thiazide diuretics may increase serum triglyceride and cholesterol levels, primarily LDL and VLDL. Whether these effects are dose-related and sustained during chronic therapy are unknown. Patients with preexisting hyperlipidemia may require closer monitoring during thiazide therapy, and adjustments made accordingly in their lipid-lowering regimenYou should also know about...
Avalide (hydrochlorothiazide / irbesartan) drug Interactions
There are 747 drug interactions with Avalide (hydrochlorothiazide / irbesartan)
Avalide (hydrochlorothiazide / irbesartan) disease Interactions
There are 14 disease interactions with Avalide (hydrochlorothiazide / irbesartan) which include:
Hypotension
Anuria
Electrolyte Losses
Liver Disease
Lupus Erythematosus
Renal Function Disorders
Chf
Renal Artery Stenosis
Renal/Liver Disease
Diabetes
Hyperlipidemia
Hyperparathyroidism
Hyperuricemia
Thyroid Function Tests
See also...
- Side Effects of Avalide (hydrochlorothiazide / irbesartan)
- Avalide (hydrochlorothiazide / irbesartan) Consumer Information
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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