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Timentin and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Timentin (clavulanate / ticarcillin).

Moderate

Ticarcillin High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

ticarcillin - sodium/potassium

Parenteral ticarcillin disodium contains approximately 120 to 150 mg (5.2 to 6.5 mEq) of sodium per each gram of ticarcillin activity. The combination, ticarcillin-clavulanate, contains approximately 109 mg (4.75 mEq) of sodium per gram of total drug. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with ticarcillin and other extended-spectrum penicillin antibiotics, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.

References

  1. Welter J, Wittman DH, Freitag V (1981) "Ticarcillin therapy of risk patients with infections due to pseudomonas aeruginosa." J Int Med Res, 9, p. 44-51
  2. Finch RA (1981) "Hypernatremia during lithium and ticarcillin therapy." South Med J, 74, p. 376-7
  3. Nanji AA, Lindsay J (1982) "Ticarcillin associated hypokalemia." Clin Biochem, 15, p. 118-9
  4. (2001) "Product Information. Ticar (ticarcillin)." SmithKline Beecham
View all 4 references

Timentin drug interactions

There are 72 drug interactions with Timentin (clavulanate / ticarcillin).

Timentin disease interactions

There are 6 disease interactions with Timentin (clavulanate / ticarcillin) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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