Tramadol Drug Interactions
Currently displaying 353 drugs known to have a moderate interaction with tramadol.
Moderate interactions with tramadol
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abiraterone
- acrivastine
- adenosine
- albuterol
- alfuzosin
- allopurinol
- aminoglutethimide
- amlodipine
- amprenavir
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- arformoterol
- armodafinil
- asciminib
- astemizole
- atazanavir
- atomoxetine
- atropine
- avacopan
- azatadine
- azelastine nasal
- azithromycin
B
- baricitinib
- belladonna
- belzutifan
- benztropine
- berotralstat
- bexarotene
- bicalutamide
- biperiden
- bisacodyl
- bitolterol
- boceprevir
- bosentan
- bosutinib
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
C
- cannabidiol
- capivasertib
- carbetapentane
- carbinoxamine
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- cetirizine
- chlophedianol
- chloramphenicol
- chlorcyclizine
- chlorpheniramine
- cilostazol
- cimetidine
- cinacalcet
- clarithromycin
- clemastine
- clidinium
- clofazimine
- clonidine
- clopidogrel
- clotrimazole
- cobicistat
- conivaptan
- cyclizine
- cyclosporine
- cyproheptadine
D
- dabrafenib
- dacomitinib
- danazol
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- degarelix
- delavirdine
- desflurane
- desmopressin
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dicyclomine
- difelikefalin
- digoxin
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxorubicin
- doxorubicin liposomal
- doxylamine
- duvelisib
E
- elafibranor
- elagolix
- eliglustat
- eluxadoline
- encorafenib
- enflurane
- entacapone
- entrectinib
- epirubicin
- eribulin
- erythromycin
- eslicarbazepine
- ethanol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etravirine
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- fesoterodine
- flavoxate
- flecainide
- flibanserin
- fluconazole
- flutamide
- formoterol
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fospropofol
- fostemsavir
G
- ganaxolone
- gilteritinib
- ginger
- ginkgo
- givinostat
- givosiran
- glasdegib
- glofitamab
- glycerin
- glycerol phenylbutyrate
- glycopyrrolate
- goldenseal
- goserelin
- griseofulvin
H
I
- idarubicin
- idelalisib
- ifosfamide
- imatinib
- indacaterol
- indinavir
- indocyanine green
- inotuzumab ozogamicin
- isavuconazonium
- isoetharine
- isoflurane
- isoniazid
- isoproterenol
- itraconazole
- ivacaftor
K
L
- lactitol
- lactulose
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lenacapavir
- lenvatinib
- lesinurad
- letermovir
- leuprolide
- levalbuterol
- levetiracetam
- levocetirizine
- levodopa
- lofexidine
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- lorlatinib
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- mavacamten
- meclizine
- melatonin
- mepenzolate
- mephenytoin
- metaproterenol
- methohexital
- methoxyflurane
- methscopolamine
- methsuximide
- methyldopa
- metreleptin
- metronidazole
- metyrosine
- mibefradil
- miconazole
- midazolam
- midostaurin
- mineral oil
- mirabegron
- mitapivat
- mitotane
- modafinil
N
O
- olodaterol
- olopatadine nasal
- olutasidenib
- omaveloxolone
- opicapone
- oritavancin
- osilodrostat
- oxaliplatin
- oxcarbazepine
- oxybutynin
- oxytocin
- ozanimod
P
- palbociclib
- paramethadione
- pazopanib
- pegvisomant
- pentamidine
- perampanel
- perflutren
- pergolide
- pexidartinib
- phenacemide
- phenindamine
- phenolphthalein
- phensuximide
- phenylbutazone
- phenytoin
- pirbuterol
- pirtobrutinib
- pitolisant
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- pralsetinib
- pramipexole
- prasugrel
- primaquine
- probucol
- procyclidine
- propafenone
- propantheline
- propofol
- pyrilamine
Q
R
- ranolazine
- relugolix
- repotrectinib
- rifabutin
- rifampin
- rifapentine
- rilpivirine
- ritlecitinib
- ritodrine
- ritonavir
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- ropinirole
- rotigotine
- rucaparib
- rufinamide
S
- salmeterol
- scopolamine
- senna
- sevoflurane
- sodium polystyrene sulfonate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotorasib
- stiripentol
- sulfinpyrazone
- sunitinib
T
- tacrolimus
- tamoxifen
- tazemetostat
- tebentafusp
- tecovirimat
- telaprevir
- telavancin
- telithromycin
- telotristat
- terbinafine
- terbutaline
- terfenadine
- tetrabenazine
- thalidomide
- thiopental
- tiagabine
- ticagrelor
- tirzepatide
- tofacitinib
- tolcapone
- tolterodine
- topiramate
- tovorafenib
- triclabendazole
- trihexyphenidyl
- trimethadione
- trimethobenzamide
- tripelennamine
- triprolidine
- triptorelin
- trofinetide
- troglitazone
- troleandomycin
- trospium
- tucatinib
U
V
- valbenazine
- valerian
- valproic acid
- vardenafil
- vasopressin
- verapamil
- vigabatrin
- viloxazine
- voclosporin
- vonoprazan
- voriconazole
- voxelotor
Z
Tramadol alcohol/food interactions
There is 1 alcohol/food interaction with tramadol.
Tramadol disease interactions
There are 12 disease interactions with tramadol which include:
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
More about tramadol
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- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.