Sertraline Drug Interactions
Currently displaying 156 drugs known to have a major interaction with sertraline.
- 156 major drug interactions
- 509 moderate drug interactions
- 5 minor drug interactions
Major interactions with sertraline
Note: Showing generic names only.
5
A
- adagrasib
- alfentanil
- almotriptan
- amiodarone
- amisulpride
- amitriptyline
- amoxapine
- amphetamine
- anagrelide
- arsenic trioxide
- astemizole
B
C
- cabozantinib
- ceritinib
- chloroquine
- cisapride
- citalopram
- clomipramine
- clozapine
- crizotinib
- cyclobenzaprine
D
- desipramine
- desvenlafaxine
- dexfenfluramine
- dextroamphetamine
- dextromethorphan
- diethylpropion
- dihydroergotamine
- disopyramide
- disulfiram
- dofetilide
- dolasetron
- doxepin
- doxepin topical
- dronedarone
- droperidol
- duloxetine
E
F
G
H
I
K
L
- lasmiditan
- lefamulin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- linezolid
- lisdexamfetamine
- lithium
- lorcaserin
M
- ma huang
- maprotiline
- mazindol
- meperidine
- mesoridazine
- methadone
- methamphetamine
- methylene blue
- metrizamide
- mifepristone
- milnacipran
- mirtazapine
- mobocertinib
- moxifloxacin
N
O
P
- pacritinib
- palonosetron
- panobinostat
- papaverine
- paroxetine
- pasireotide
- pentazocine
- phendimetrazine
- phenelzine
- phentermine
- phenylpropanolamine
- pimozide
- plasminogen, human
- ponesimod
- procainamide
- procarbazine
- propoxyphene
- protriptyline
Q
R
S
- saquinavir
- selegiline
- selpercatinib
- sibutramine
- siponimod
- sodium oxybate
- sotalol
- sparfloxacin
- st. john's wort
- sufentanil
- sumatriptan
T
- tamoxifen
- tapentadol
- thioridazine
- toremifene
- tramadol
- tranylcypromine
- trazodone
- trimipramine
- tryptophan
V
Z
Sertraline alcohol/food interactions
There is 1 alcohol/food interaction with sertraline.
Sertraline disease interactions
There are 10 disease interactions with sertraline which include:
- depression
- hyponatremia
- glaucoma
- liver disease
- mania
- platelet function
- seizure disorders
- SIADH
- renal dysfunction
- weight loss
More about sertraline
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- Drug class: selective serotonin reuptake inhibitors
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.