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Sertraline Dosage

Medically reviewed by Drugs.com. Last updated on Feb 9, 2023.

Applies to the following strengths: 20 mg/mL; 50 mg; 100 mg; 25 mg; 150 mg; 200 mg

Usual Adult Dose for Depression

Initial dose: 50 mg orally once a day
Maintenance Dose: 50 to 200 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Obsessive Compulsive Disorder

Initial dose: 50 mg orally once a day
Maintenance Dose: 50 to 200 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Panic Disorder

Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day
Maintenance dose: 50 to 200 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Post Traumatic Stress Disorder

Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day
Maintenance dose: 50 to 200 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Social Anxiety Disorder

Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day
Maintenance dose: 50 to 200 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Premenstrual Dysphoric Disorder

Continuous regimen:


Cyclic regimen:

Comments:

Treatment of premenstrual dysphoric disorder (PMDD)

Usual Pediatric Dose for Obsessive Compulsive Disorder

6 to 12 years:


13 to 17 years:

Comments:

Use: Treatment of OCD

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Mild liver dysfunction (Child-Pugh 5 to 6): Patients should be given 50% of the initial and maintenance doses.
Moderate to severe liver dysfunction (Child-Pugh 7 to 15): Not recommended.

Dose Adjustments

Dose adjustments should be made to maintain patients on the lowest effective dose.

Switching from:


Treatment withdrawal:

Precautions

US BOXED WARNINGS:
SUICIDAL THOUGHTS AND BEHAVIORS:


Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Reconstitution/preparation techniques:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.