Drug Interactions between lorlatinib and Versed
This report displays the potential drug interactions for the following 2 drugs:
- lorlatinib
- Versed (midazolam)
Interactions between your drugs
midazolam lorlatinib
Applies to: Versed (midazolam) and lorlatinib
Lorlatinib may reduce the blood levels and effects of midazolam. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Let your doctor know if midazolam becomes less effective or is no longer controlling your symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
lorlatinib food
Applies to: lorlatinib
Do not consume grapefruit or grapefruit juice during treatment with lorlatinib. Grapefruit juice can significantly increase the blood levels and effects of lorlatinib, which may result in a greater risk of side effects. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
midazolam food
Applies to: Versed (midazolam)
Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking midazolam. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take midazolam with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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