Lorlatinib Interactions
There are 510 drugs known to interact with lorlatinib, along with 8 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 127 are major, 372 are moderate, and 11 are minor.
- View all 510 medications that may interact with lorlatinib
- View lorlatinib alcohol/food interactions (3)
- View lorlatinib disease interactions (8)
Most frequently checked interactions
View interaction reports for lorlatinib and the medicines listed below.
- Aleve (naproxen)
- Aridol (mannitol)
- Ativan (lorazepam)
- Avastin (bevacizumab)
- Brevital Sodium (methohexital)
- Cerebyx (fosphenytoin)
- Clobex (clobetasol topical)
- CoQ10 (ubiquinone)
- Cosentyx (secukinumab)
- Coumadin (warfarin)
- Decadron with Xylocaine (dexamethasone / lidocaine)
- DHEA (dehydroepiandrosterone)
- Dilantin (phenytoin)
- Durezol (difluprednate ophthalmic)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- FUDR (floxuridine)
- GastroMARK (ferumoxsil)
- Geref Diagnostic (sermorelin)
- Ginkgo Biloba (ginkgo)
- Januvia (sitagliptin)
- Keytruda (pembrolizumab)
- Lexapro (escitalopram)
- Paracetamol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin K2 (menaquinone)
- Xalkori (crizotinib)
- Xarelto (rivaroxaban)
Lorlatinib alcohol/food interactions
There are 3 alcohol/food interactions with lorlatinib.
Lorlatinib disease interactions
There are 8 disease interactions with lorlatinib which include:
- atrioventricular block
- CNS effects
- hepatotoxicity/hepatic impairment
- hyperglycemia
- hyperlipidemia
- hypertension
- interstitial lung disease
- severe renal impairment
Report options
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More about lorlatinib
- lorlatinib consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
