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Drug Interactions between Gani-Tuss-DM NR and zuranolone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

dextromethorphan zuranolone

Applies to: Gani-Tuss-DM NR (dextromethorphan / guaifenesin) and zuranolone

Zuranolone may cause sedation, dizziness, confusion, and trouble walking. The risk and/or severity may be increased when combined with other antidepressants or other medications that can also cause sedation. Let your doctor know prior to receiving zuranolone if you are currently using alcohol or receiving treatment with dextromethorphan, as you may be more likely to experience sedation-related side effects. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Do not drive, operate machinery, or engage in potentially hazardous activities requiring mental alertness and motor coordination until at least 12 hours after taking zuranolone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

dextromethorphan food

Applies to: Gani-Tuss-DM NR (dextromethorphan / guaifenesin)

Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan. Do not use more than the recommended dose of dextromethorphan, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

zuranolone food

Applies to: zuranolone

Zuranolone must be taken with fat-containing food to ensure adequate absorption of the mediation. It is also best to avoid or limit the consumption of alcohol, as it can increase drowsiness or other nervous system side effects of zuranolone. You should also avoid activities requiring mental alertness such as driving or operating hazardous machinery until at least 12 hours after taking zuranolone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer