Drug Interactions between elexacaftor / ivacaftor / tezacaftor and Linzess
This report displays the potential drug interactions for the following 2 drugs:
- elexacaftor/ivacaftor/tezacaftor
- Linzess (linaclotide)
Interactions between your drugs
No interactions were found between elexacaftor / ivacaftor / tezacaftor and Linzess. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
elexacaftor / ivacaftor / tezacaftor
A total of 439 drugs are known to interact with elexacaftor / ivacaftor / tezacaftor.
- Elexacaftor / ivacaftor / tezacaftor is in the drug class CFTR combinations.
- Elexacaftor / ivacaftor / tezacaftor is used to treat Cystic Fibrosis.
Linzess
A total of 59 drugs are known to interact with Linzess.
- Linzess is in the drug class guanylate cyclase-C agonists.
- Linzess is used to treat the following conditions:
Drug and food interactions
ivacaftor food
Applies to: elexacaftor / ivacaftor / tezacaftor
Ivacaftor should be taken with fat-containing foods such as eggs, avocados, nuts, meat, butter, peanut butter, cheese pizza, and whole-milk dairy products to help with its absorption. Do not consume grapefruit juice or any food that contains grapefruit or Seville oranges during treatment with ivacaftor unless directed otherwise by your doctor. Grapefruit juice can significantly increase the blood levels of ivacaftor. This may increase the risk and/or severity of serious side effects such as liver damage. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
linaclotide food
Applies to: Linzess (linaclotide)
Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea. To reduce the risk of gastrointestinal intolerance, linaclotide should be taken on an empty stomach at least 30 minutes prior to the first meal of the day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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