Ibuprofen PM Interactions
There are 747 drugs known to interact with Ibuprofen PM (diphenhydramine/ibuprofen), along with 21 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 111 are major, 624 are moderate, and 12 are minor.
- View all 747 medications that may interact with Ibuprofen PM
- View Ibuprofen PM alcohol/food interactions (3)
- View Ibuprofen PM disease interactions (21)
Most frequently checked interactions
View interaction reports for Ibuprofen PM (diphenhydramine / ibuprofen) and the medicines listed below.
- acetaminophen
- albuterol
- amitriptyline
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- clonazepam
- cyclobenzaprine
- furosemide
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- melatonin
- metformin
- naproxen
- omeprazole
- pantoprazole
- Paracetamol (acetaminophen)
- prednisone
- sertraline
- simvastatin
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
Ibuprofen PM alcohol/food interactions
There are 3 alcohol/food interactions with Ibuprofen PM (diphenhydramine / ibuprofen).
Ibuprofen PM disease interactions
There are 21 disease interactions with Ibuprofen PM (diphenhydramine / ibuprofen) which include:
- depression
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- PKU
- anemia
- heart failure
- hepatotoxicity
- hyperkalemia
- hypertension
- platelet aggregation inhibition
More about Ibuprofen PM (diphenhydramine / ibuprofen)
- Ibuprofen PM consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (2)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.