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Drug Interactions between deferiprone and Galzin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

zinc acetate deferiprone

Applies to: Galzin (zinc acetate) and deferiprone

ADJUST DOSING INTERVAL: Deferiprone has the potential to bind polyvalent cations such as aluminum, iron and zinc, which may reduce its effectiveness. However, concurrent use with foods, mineral supplements, or antacids that contain polyvalent cations has not been studied.

MANAGEMENT: A minimum 4-hour interval is recommended between the administration of deferiprone and mineral supplements or oral medications that contain antacids (e.g., didanosine buffered tablets or pediatric oral solution) or other polyvalent cations.

References

  1. (2011) "Product Information. Ferriprox (deferiprone)." ApoPharma USA Inc

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Drug and food interactions

Moderate

zinc acetate food

Applies to: Galzin (zinc acetate)

ADJUST DOSING INTERVAL: The presence of certain foods (e.g., bread, bran, hard boiled eggs, coffee, and milk) may significantly delay the absorption of zinc acetate. Fibres, phytates, and other substances in food prevent zinc from entering intestinal cells by binding with it. Protein does not appear to interfere with its absorption.

MANAGEMENT: Zinc acetate should preferably be taken on an empty stomach, at least one hour before or two to three hours after meals. It may be taken with small amounts of protein such as meat.

References

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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