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Drug Interactions between calcipotriene topical and Emcyt

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

estramustine calcipotriene topical

Applies to: Emcyt (estramustine) and calcipotriene topical

MONITOR: Elevations in serum calcium levels have been observed in patients treated with topical vitamin D analogs. Concomitant use with systemic vitamin D products, calcium supplements, or other agents that can increase serum calcium concentrations such as thiazide diuretics, estrogens, anabolic steroids, and parathyroid hormone or parathyroid hormone analogs may increase the risk of clinically significant hypercalcemia.

MANAGEMENT: Calcium and vitamin D status should be monitored closely when topical vitamin D analogs are used in combination with systemic vitamin D products or other agents that can increase serum calcium levels.

References

  1. "Product Information. Dovonex (calcipotriene topical)." Westwood Squibb Pharmaceutical Corporation
  2. (2009) "Product Information. Vectical (calcitriol topical)." Galderma Laboratories Inc
  3. (2022) "Product Information. Silkis (calcitriol topical)." Galderma (UK) Ltd

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Drug and food interactions

Moderate

estramustine food

Applies to: Emcyt (estramustine)

ADJUST DOSING INTERVAL: Food and milk may significantly decrease serum concentrations of estramustine. The mechanism of the interaction is not known.

MANAGEMENT: It is recommended that estramustine be taken at least 1 hour before or 2 hours after meals, and that it not be coadministered with milk, or calcium containing products.

References

  1. (2001) "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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