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Antimetabolites

What are Antimetabolites?

Antimetabolites are drugs that interfere with one or more enzymes or their reactions that are necessary for DNA synthesis. They affect DNA synthesis by acting as a substitute to the actual metabolites that would be used in the normal metabolism (for example antifolates interfere with the use of folic acid).

Antimetabolites are drugs used in cancer chemotherapy. Cancer cells divide more rapidly compared to normal cells so antimetabolites affect cancer cell replication more than they affect normal cell replication.

List of Antimetabolites

View by  Brand | Generic
Drug Name Avg. Rating Reviews
pemetrexed systemic (Pro)
9.0
2 reviews
cladribine systemic (Pro)
8.7
8 reviews
gemcitabine systemic (Pro)
8.0
7 reviews
hydroxyurea systemic (Pro)
7.0
43 reviews
methotrexate systemic (Pro)
6.6
332 reviews
capecitabine systemic (Pro)
6.6
57 reviews
mercaptopurine systemic (Pro)
6.2
31 reviews
fludarabine systemic (Pro)
6.0
1 review
fluorouracil systemic (Pro)
3.7
3 reviews
pralatrexate systemic (Pro)
1.0
1 review
thioguanine systemic (Pro)
No reviews
nelarabine systemic (Pro)
No reviews
floxuridine systemic (Pro)
No reviews
decitabine systemic (Pro)
No reviews
cytarabine systemic (Pro)
No reviews
cytarabine liposomal systemic
No reviews
clofarabine systemic (Pro)
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.