Scopolamine Dosage

This dosage information may not include all the information needed to use Scopolamine safely and effectively. See additional information for Scopolamine.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nausea/Vomiting

General antiemetic use: 0.3 to 0.65 mg administered IV, intramuscularly or subcutaneously every 6 to 8 hours as needed.

Post-operative nausea and vomiting use: apply one scopolamine 1.5 mg transdermal disc behind the ear the evening before the scheduled surgery. The disc should remain in place for 24 hours after surgery before discarding.

If using scopolamine transdermal on an obstetrics patient, apply the disc one hour prior to scheduled Cesarean section to limit exposure to the infant.

Usual Adult Dose for Motion Sickness

Apply one scopolamine 1.5 mg transdermal disc behind the ear at least 4 hours prior to exposure every 3 days as needed.

Usual Adult Dose for Parkinsonian Tremor

0.4 to 0.8 mg orally every 8 hours as needed.

Usual Pediatric Dose for Nausea/Vomiting

1 to 12 years: 6 mcg/kg/dose (maximum dose: 0.3 mg/dose) administered IV, IM or subcutaneous every 6 to 8 hours as needed.

Usual Pediatric Dose for Motion Sickness

Greater than 12 years: apply one scopolamine 1.5 mg transdermal disc behind the ear at least 4 hours prior to exposure every 3 days as needed.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

As with other anticholinergic agents, scopolamine is contraindicated for patients with angle-closure glaucoma, prostatic hypertrophy, and pyloric obstruction. It should not be administered to patients with impaired hepatic or renal function.

Scopolamine may cause drowsiness, confusion, and disorientation. The elderly may be particularly sensitive to these effects. All patients should be cautioned against engaging in activities which require mental alertness, such as driving or operating dangerous machinery, while using the scopolamine transdermal patch. The concomitant use of alcohol or other agents possessing CNS depressant activity should be avoided if possible.

Scopolamine may aggravate seizures (although this association has been disputed) and psychoses and should be used cautiously in patients with a history of such disorders.

Use with caution in patients with cardiac disease and in the elderly.

The safety and efficacy of scopolamine in children have not been determined.

Dialysis

Data not available

Other Comments

Scopolamine transdermal patches contain residual drug when removed after being applied for 72 hours. Patients should wash their hands well with soap and water to prevent accidental transfer of scopolamine to eyes or mucosal surfaces. Once removed, the patch should be folded against itself such that the adhesive side containing residual drug is not accessible.

Only one transdermal patch should be on the patient at any given time during therapy; remove the used disc prior to placing a fresh disc on the skin.

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