Moricizine Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Ventricular Tachycardia

Initial dose: 200 mg orally every 8 hours.
Maintenance dose: 200-300 mg orally every 8 hours.

Renal Dose Adjustments

Patients with significant renal dysfunction should be started at 600mg/day or lower and monitored closely, including measurement of EKG intervals, before dosage adjustment.

Liver Dose Adjustments

Patients with severe liver disease should be administered moricizine with particular care, if at all. Patients with hepatic disease may be started at 600 mg/day or lower and monitored closely, including measurement of EKG intervals, before dosage adjustment.

Dose Adjustments

The dose may be titrated upwards every 3 days to 250 mg every 8 hours, then 300 mg every 8 hours.

Precautions

Patients should be monitored on telemetry when first started on moricizine and for 48 hours after steady state. The QTc interval should be checked on a regular basis and with any increase in dose.

Other Comments

The maximum recommended daily dose is 300 mg every 8 hours.

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