Medication Guide App

Mebendazole Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for Angiostrongylosis

100 mg orally twice a day for 5 days.

Usual Adult Dose for Ascariasis

100 mg orally twice a day for 3 days. If biliary obstruction is also present, piperazine citrate 150 mg/kg initially, followed by 65 mg/kg every 12 hours for 6 doses by nasogastric tube is also recommended.

Usual Adult Dose for Capillariasis

200 mg orally twice a day for 20 days. Relapses may be treated with prolonged courses of therapy.

Usual Adult Dose for Trichostrongylosis

100 mg orally twice a day for 3 days.

Usual Adult Dose for Filariasis

100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Mansonella perstans infection - 100 mg twice daily for 30 days.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

100 mg orally twice a day for 3 days.

Usual Adult Dose for Whipworm Infection (Trichuris trichiura)

100 mg orally twice a day for 3 days.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Usual Adult Dose for Trichinosis

200 to 400 mg orally three times a day for 3 days, then 400 to 500 mg three times a day for 10 days. Concomitant steroid therapy may be administered if patient is symptomatic.

Usual Adult Dose for Visceral Larva Migrans (Toxicariasis)

100 to 200 mg orally twice daily for 5 days. Coadministration of anti-inflammatory agents might be considered.

Usual Adult Dose for Echinococcus Infection

Case Series (n=769)
Hepatic Cystic infection - Larval (tissue stage): 40 to 50 mg/kg per day, administered in three divided doses, in conjunction with percutaneous aspiration-injection-reaspiration (PAIR) drainage, 1 week before and 4 weeks after PAIR drainage.

Usual Adult Dose for Hydatid Disease

Case Series (n=769)
Hepatic Cystic infection - Larval (tissue stage): 40 to 50 mg/kg per day, administered in three divided doses, in conjunction with percutaneous aspiration-injection-reaspiration (PAIR) drainage, 1 week before and 4 weeks after PAIR drainage.

Usual Adult Dose for Dracunculiasis

400 to 800 mg per day for 6 days.

Usual Pediatric Dose for Angiostrongylosis

Greater than or equal to 2 years: 100 mg orally twice a day for 5 days.

Usual Pediatric Dose for Ascariasis

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days. If biliary obstruction is also present, piperazine citrate 150 mg/kg initially, followed by 65 mg/kg every 12 hours for 6 doses by nasogastric tube is also recommended.

Usual Pediatric Dose for Capillariasis

Greater than or equal to 2 years: 200 mg orally twice a day for 20 days. Relapses may be treated with prolonged courses of therapy.

Usual Pediatric Dose for Filariasis

Greater than or equal to 2 years: 100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Mansonella perstans infection - 100 mg twice daily for 30 days.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days.

Usual Pediatric Dose for Whipworm Infection (Trichuris trichiura)

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

Greater than or equal to 2 years: 100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Usual Pediatric Dose for Trichinosis

Greater than or equal to 2 years: 200 to 400 mg orally three times daily for 3 days, then 400 to 500 mg three times daily for 10 days. Steroids may be administered if patient is symptomatic.

Cases (n=23) - Trichinella nativa infection:
1 to 14 years: 200 mg orally three times daily for the first 3 days, then 400 mg orally three times daily for another 11 days. Concomitant steroid therapy may be administered if patient is symptomatic.

Usual Pediatric Dose for Visceral Larva Migrans (Toxicariasis)

Greater than or equal to 2 years: 100 to 200 mg orally twice daily for 5 days. Coadministration of anti-inflammatory agents might be considered.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Dose reductions may be necessary in patients with liver dysfunction.

Precautions

Neutropenia and agranulocytosis have been rarely reported with prolonged administration of mebendazole and at dosages substantially above those recommended.

The manufacturer recommends periodic assessment of organ system functions, including hematopoietic and hepatic, during prolonged mebendazole therapy.

There is no evidence that mebendazole, even at high doses, is effective for hydatid disease.

The safety of mebendazole in children younger than 2 years has not been established.

Dialysis

Mebendazole is not dialyzable.

Other Comments

The tablet may be chewed, swallowed, or crushed and mixed with food.

If the patient is not cured 3 weeks after the start of treatment, a second course of treatment is advised.

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