Mebendazole Pregnancy and Breastfeeding Warnings
Mebendazole is also known as: Vermox
Mebendazole Pregnancy Warnings
Mebendazole has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of fetotoxicity and teratogenicity. There are no controlled data in human pregnancy. However, mebendazole has been used during pregnancy without evidence of fetal harm. Mebendazole is only recommended for use during pregnancy when benefit outweighs risk.
Mebendazole Breastfeeding Warnings
Limited data suggest that mebendazole is poorly excreted into breast milk. Mebendazole is poorly absorbed orally; it is unlikely to adversely affect the breastfed infant or milk production. An informal consultation group to the World Health Organization decided that a single oral dose of mebendazole can be given to lactating women. In 1 report, the peak milk level was 6 mcg/L after a single 100 mg oral dose of mebendazole was given to a nursing mother (time postpartum not stated). Mebendazole was no longer detectable (less than 1 mcg/L) in milk 13.25 hours after the dose. Starting the first day postpartum, 1 woman was given mebendazole 100 mg orally twice a day for 3 days. When measured after treatment (exact timing not stated), mebendazole was undetectable (less than 20 mcg/L) in milk. The authors stated that this result was similar to those reported by the manufacturer and that the infant probably absorbed negligible mebendazole from breast milk.
Caution is recommended. Excreted into human milk: Yes (poorly) Excreted into animal milk: Unknown The effects in the nursing infant are unknown.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.