Magnesium Oxide Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Duodenal Ulcer

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Dyspepsia

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Gastric Ulcer

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Gastroesophageal Reflux Disease

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Hypomagnesemia

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Pathological Hypersecretory Disorder

Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Renal Stones

140 to 420 mg (84 to 252 mg elemental magnesium) orally once a day. Magnesium oxide has also been used in combination with pyridoxine to prevent recurrence of calcium oxalate renal calculi.

Usual Adult Dose for Constipation

Oral:
Caplets (500 mg): 2 to 4 caplets orally daily with a full 8 ounce glass of liquid.

Caplets may be taken all at bedtime or separately throughout the day.

Usual Pediatric Dose for Constipation

Oral:
12 years or older:
Caplets (500 mg): 2 to 4 caplets orally daily with a full 8 ounce glass of liquid.

Caplets may be taken all at bedtime or separately throughout the day.

Renal Dose Adjustments

Do not use without physician supervision in patients with renal impairment due to increased risk of hypermagnesemia.

Liver Dose Adjustments

Data not available

Dose Adjustments

The dose may be titrated as needed and tolerated to replete magnesium levels in nonemergent situations. Therapy should be reevaluated in 2 weeks or less.

Precautions

Because magnesium is primarily eliminated by the kidney, there is significant risk of hypermagnesemia in patients with renal dysfunction.

Dialysis

Data not available; however, use of magnesium salts is generally contraindicated in renal failure.

Other Comments

Coexistent hypocalcemia and hypokalemia may correct upon repletion of magnesium.

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