Hydrochlorothiazide / Triamterene Dosage

This dosage information may not include all the information needed to use Hydrochlorothiazide / Triamterene safely and effectively. See additional information for Hydrochlorothiazide / Triamterene.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Edema

1 to 2 tablets or capsules (hydrochlorothiazide/triamterene 25 mg-37.5 mg) orally once a day or
1 to 2 capsules (hydrochlorothiazide/triamterene 25 mg-50 mg) orally once a day after meals or
1 tablet (hydrochlorothiazide/triamterene 50 mg-75 mg) orally once a day.

Usual Adult Dose for Hypertension

1 to 2 tablets or capsules (hydrochlorothiazide/triamterene 25 mg-37.5 mg) orally once a day or
1 to 2 capsules (hydrochlorothiazide/triamterene 25 mg-50 mg) orally once a day after meals or
1 tablet (hydrochlorothiazide/triamterene 50 mg-75 mg) orally once a day.

Renal Dose Adjustments

Hydrochlorothiazide is generally not effective in patients with creatinine clearance less than 25 mL/min. Thiazides should be used with caution in patients with severe renal disease.

Liver Dose Adjustments

1 tablet or capsule (hydrochlorothiazide/triamterene 25 mg-37.5 mg) orally once a day or
1 capsule (hydrochlorothiazide/triamterene 25 mg-50 mg) orally once a day after meals or
1 tablet (hydrochlorothiazide/triamterene 50 mg-75 mg) orally once a day.
Thiazides should be used with caution in patients with impaired hepatic function.

Dose Adjustments

Doses containing 25 mg of hydrochlorothiazide may be doubled as needed at least 3 days after initial therapy.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available. Although triamterene is 67% protein-bound, there may be some benefit to dialysis in cases of overdosage.

Other Comments

The maximum recommended dosages are:
2 tablets or capsules (HCTZ/triamterene 25 mg-37.5 mg) orally once a day or
2 capsules (HCTZ/triamterene 25 mg-50 mg) orally twice a day after meals or
1 tablet (HCTZ/triamterene 50 mg-75 mg) orally once a day.

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