Felodipine Dosage

This dosage information may not include all the information needed to use Felodipine safely and effectively. See additional information for Felodipine.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Initial dose: 5 mg orally once a day
Maintenance dose: 2.5 to 10 mg orally once a day

National Institutes of Health (NIH) and National Heart, Lung, and Blood Institute (NHLBI) recommendations:
Maintenance dose: 2.5 to 20 mg orally once a day

Usual Geriatric Dose for Hypertension

Initial dose: 2.5 mg orally once a day
Maintenance dose: 2.5 to 10 mg orally once a day

Usual Pediatric Dose for Hypertension

(Not approved by FDA)

NIH and NHLBI recommendations:
1 year or older:
Initial dose: 2.5 mg orally once a day
Maintenance dose: 2.5 to 10 mg orally once a day

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Impaired liver function:
Initial dose: 2.5 mg orally once a day
Maintenance dose: 2.5 to 10 mg orally once a day

Dose Adjustments

In general, the dosage should be adjusted at intervals of 2 weeks or longer, depending on patient response and tolerance.

Precautions

In clinical trials, doses above 10 mg/day showed an increased blood pressure response but a large increase in the rate of peripheral edema and other vasodilatory side effects.

Blood pressure should be carefully monitored during initial titration and any subsequent dosage adjustment, especially in geriatric patients and patients with impaired liver function. Felodipine should be used with caution in these patients.

Safety has not been established in patients with heart failure. Felodipine should be used with caution in patients with heart failure or compromised ventricular function, especially when coadministered with a beta-blocker.

Concomitant use of grapefruit juice should generally be avoided.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

No adjustment recommended.

Other Comments

Felodipine should regularly be taken either without food or with a light meal. The tablets should be swallowed whole and not crushed or chewed.

Mild gingival hyperplasia has been reported with felodipine. Good dental hygiene is recommended to decrease its incidence and severity.

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