Ethosuximide Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Seizures

Initial dose: 500 mg (10 mL) orally daily
Maintenance dose: Dosage may be increased by small increments, for example 250 mg daily every 4 to 7 days, until optimal seizure control with minimal side effects is achieved. Dosages greater than 1.5 g per day, in divided doses, should be administered only under strict supervision of a physician.

Usual Pediatric Dose for Seizures

3 to 6 years:
Initial dose: 250 mg (5 mL) orally daily
Maintenance dose: Dosage may be increased by small increments, for example 250 mg daily every 4 to 7 days, until optimal seizure control with minimal side effects is achieved. For most pediatric patients the optimal dose is 20 mg/kg/day in divided doses. Dosages greater than 1.5 g per day, in divided doses, should be administered only under close supervision by a physician.

> 6 to 18 years:
Initial dose: 500 mg (10 mL) orally daily
Maintenance dose: Dosage may be increased by small increments, for example 250 mg daily every 4 to 7 days, until optimal seizure control with minimal side effects is achieved. For most pediatric patients the optimal dose is 20 mg/kg/day in divided doses. Dosages greater than 1.5 g per day, in divided doses, should be administered only under close supervision by a physician.

Renal Dose Adjustments

Administer with extreme caution in patients with renal dysfunction.

Liver Dose Adjustments

Administer with extreme caution in patients with liver dysfunction

Precautions

Monotherapy with ethosuximide in patients with mixed types of epilepsy may increase the probability of grand mal seizures in some patients.

Dosage changes of ethosuximide, as well as, the addition and/or elimination of other medications should be done slowly. In addition, withdrawal of ethosuximide therapy should be done gradually.

Ethosuximide may impair the mental and/or physical abilities necessary for potentially hazardous tasks such as driving or operating machinery.

Dialysis

Data not available

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