Generic Name: ethosuximide (ETH-oh-SUX-i-mide)
Brand Name: Zarontin
Ethosuximide solution is used for:
Controlling a certain type of seizures (absence or petit mal seizures). It may also be used for other conditions as determined by your doctor.
Ethosuximide solution is an anticonvulsant. It acts in the brain to reduce the number of seizures.
Do NOT use ethosuximide solution if:
- you are allergic to any ingredient in ethosuximide solution or similar medicines (eg, methsuximide)
Contact your doctor or health care provider right away if any of these apply to you.
Before using ethosuximide solution:
Some medical conditions may interact with ethosuximide solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney disease, lupus, or the blood disorder porphyria
- if you have a history of mood or mental problems (eg, depression), or suicidal thoughts or attempts
Some MEDICINES MAY INTERACT with ethosuximide solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Hydantoins (eg, phenytoin) because the risk of their side effects may be increased by ethosuximide solution
- Valproic acid because it may affect the amount of ethosuximide solution in your blood
This may not be a complete list of all interactions that may occur. Ask your health care provider if ethosuximide solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use ethosuximide solution:
Use ethosuximide solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Ethosuximide solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get ethosuximide solution refilled.
- Take ethosuximide solution by mouth with or without food.
- Do not change the dose of ethosuximide solution or stop this or other medicines without checking with your doctor. If this needs to be done, it should be done slowly as directed by your doctor. Suddenly stopping ethosuximide solution may increase the risk of seizures.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Taking ethosuximide solution at the same time each day will help you remember to take it. Take ethosuximide solution on a regular schedule to get the most benefit from it.
- Continue to take ethosuximide solution even if you feel well. Do not miss any doses.
- If you miss a dose of ethosuximide solution, take it as soon as possible. If it is almost time for you next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use ethosuximide solution.
Important safety information:
- Ethosuximide solution may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use ethosuximide solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT take more than the recommended dose or change your dose without checking with your doctor.
- Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using ethosuximide solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Ethosuximide solution may cause swelling and tenderness of your gums. Proper dental care is important while taking ethosuximide solution. Brush and floss your teeth on a regular schedule and have regular dental checkups.
- Patients who take ethosuximide solution may be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take ethosuximide solution closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Serious and sometimes fatal rashes have been reported with the use of ethosuximide solution. Most of these developed within the first 28 days after starting treatment. However, they may occur at any time during treatment. Contact your doctor at once if you develop rash symptoms, including red, swollen, blistered, or peeling skin.
- Lab tests, including complete blood cell counts, liver function, and kidney function tests, may be performed while you use ethosuximide solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Ethosuximide solution should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using ethosuximide solution while you are pregnant. Ethosuximide solution is found in breast milk. If you are or will be breast-feeding while you use ethosuximide solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of ethosuximide solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; dizziness or light-headedness; drowsiness; headache; hiccups; loss of appetite; mild stomach pain; nausea; stomach upset or cramps; tiredness; vomiting; weight loss.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; sores in your mouth); decreased coordination; decreased urination; hallucinations; lupus symptoms (eg, butterfly-shaped rash on the face, chest pain, joint pain or swelling, muscle pain); new or worsening mood, mental, or behavior changes (eg, depression); new or worsening seizures; nightmares; red or purple spots on your body; red, swollen, blistered, or peeling skin; signs of infection (eg, fever, chills, sore throat); suicidal thoughts or attempts; swollen lymph nodes; symptoms of liver problems (eg, dark urine, pale stools, persistent loss of appetite, stomach pain, yellowing or the skin or eyes); trouble concentrating; trouble sleeping; unsteadiness when walking; unusual bruising or bleeding (eg, bleeding gums, nosebleeds); unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; nausea; severe drowsiness; slow or shallow breathing; vomiting.Proper storage of ethosuximide solution:
Store ethosuximide solution between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not freeze. Keep in a tightly closed container. Keep ethosuximide solution out of the reach of children and away from pets.
- If you have any questions about ethosuximide solution, please talk with your doctor, pharmacist, or other health care provider.
- Ethosuximide solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take ethosuximide solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ethosuximide solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ethosuximide solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using ethosuximide solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.