Dimethyl Sulfoxide Dosage

Medically reviewed by Drugs.com. Last updated on Sep 11, 2023.

Applies to the following strengths: 50%; 99%

Usual Adult Dose for:

Cystitis

Additional dosage information:

Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments

Usual Adult Dose for Cystitis

Instill 50 mL into the bladder by catheter or asepto syringe; allow to remain for 15 minutes; the medication is expelled by spontaneous voiding; repeat every 2 weeks until maximum symptomatic relief is obtained

Duration of therapy: Time intervals between therapy may be increased as

Use: For the symptomatic relief of patients with interstitial cystitis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Apply an analgesic lubricant gel to urethra prior to insertion of catheter to avoid spasm.
Administration of an oral analgesic medication or suppository containing belladonna and opium prior to instillation can reduce bladder spasms.
The initial treatment, and possibly the second and third should be done under anesthesia (saddle block) in patients with severe interstitial cystitis and very sensitive bladders.

Storage requirements:

Store at 20C to 25C (68F to 77F).
Protect from strong light.

Monitoring:

Approximately every 6 months patients receiving this drug should have a biochemical screening, particularly liver and renal function tests, and complete blood count.