Medication Guide App

Dimenhydrinate Dosage

This dosage information may not include all the information needed to use Dimenhydrinate safely and effectively. See additional information for Dimenhydrinate.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Motion Sickness

50 to 100 mg, orally, IM or IV, every 4 to 6 hours, to a maximum of 400 mg in 24 hours. The first dose should be taken 30 to 60 minutes before starting activity.

Usual Pediatric Dose for Motion Sickness

Greater than or equal to 2 to less than 6 years: 12.5 to 25 mg orally every 6 to 8 hours, to a maximum of 75 mg in 24 hours.

Greater than or equal to 6 to less than 12 years: 25 to 50 mg orally every 6 to 8 hours, to a maximum of 150 mg in 24 hours.

Greater than 12 years: 25 to 100 mg orally 30 to 60 minutes before starting activity, then 25 to 100 mg every 4 to 6 hours, to maximum of 400 mg in 24 hours.

The first dose should be taken 30 to 60 minutes before starting activity.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Dimenhydrinate is contraindicated in neonates.

For infants and children especially, antihistamines in overdose may cause hallucinations, convulsions, or death. As in adults, antihistamines may reduce mental alertness in pediatric patients. They may produce excitation, particularly, in young children.

Due to the anticholinergic effect of dimenhydrinate, it should be used with caution in patients with stenosing peptic ulcer, narrow-angle glaucoma, pyloroduodenal obstruction, prostatic hypertrophy, or bladder neck obstructions. It should also be used with caution in patients with increased intraocular pressure, seizure disorders, hyperthyroidism, hypertension, or cardiovascular disease. Patients should be advised to consult with their doctor before starting therapy with dimenhydrinate if they have breathing problems (emphysema, or chronic bronchitis).

Caution should be used when administering dimenhydrinate to patients with seizure disorders.

Patients should be warned of the sedative effects of dimenhydrinate, and advised not to take this drug with alcohol.

Dimenhydrinates sedative effects may impair the patient's ability to perform hazardous activities that require mental alertness and physical coordination. Caution should be used when driving a motor vehicle or operating machinery.

Some of the chewable products available contain aspartame, which is metabolized to phenylalanine following oral administration. Patients with phenylketonuria or others that need to restrict their intake of phenylalanine should be warned.

Tartrazine (FD&C yellow No 5) may be found in some chewable tablets. It may trigger an allergic reaction in some susceptible individuals, particularly in patients who are sensitive to aspirin.

Dialysis

Data not available

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