Codeine / Guaifenesin Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough

Oral liquid:
10 mg-100 mg/5 mL or 10 mg-200mg/5 mL: 10 mL orally every 4 hours as needed, not to exceed 60 mL/day.
10 mg-300 mg/5 mL: 5 mL orally every 4 hours as needed, not to exceed 40 mL/day.
7.5 mg-225 mg/5 mL oral liquid: 5 mL to 7.5 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
6.3 mg-100 mg/5 mL oral liquid: 15 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
8 mg-200 mg/5 mL oral liquid: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.


Oral tablet:
10 mg-300 mg, 10 mg-400 mg or 20 mg-400 mg: 1 tablet orally every 4 hours as needed, not to exceed 6 tablets/day.

Oral Capsule:
9 mg-200 mg: 2 capsules orally every 4 hours, not to exceed 12 capsules in a 24 hour period.

Usual Pediatric Dose for Cough

2 to 5 years: 5 mL syrup (2.5 mg-75 mg/5 mL) orally every 4 hours as needed, not to exceed 30 mL/day.

2 years:
10 mg-300 mg/5 mL liquid: 1.5 mL orally every 4 to 6 hours as needed, not to exceed 6 mL/day

3 years:
10 mg-300 mg/5 mL liquid: 1.75 mL orally every 4 to 6 hours as needed, not to exceed 7 mL/day

4 years:
10 mg-300 mg/5 mL liquid: 2 mL orally every 4 to 6 hours as needed, not to exceed 8 mL/day

5 years:
10 mg-300 mg/5 mL liquid: 2.25 mL orally every 4 to 6 hours as needed, not to exceed 9 mL/day

6 to 11 years:
10 mg-100 mg/5 mL or 10 mg-200 mg/5 mL syrup: 5 mL orally every 4 hours as needed, not to exceed 30 mL/day
10 mg-300 mg/5 mL liquid: 2.5 mL orally every 4 hours as needed, not to exceed 20 mL/day
10 mg-400 mg, or 20 mg-400 mg tablet: 1 tablet orally every 4 hours as needed, not to exceed 6 tablets/day.
7.5 mg-225 mg/5 mL oral liquid: 5 mL to 7.5 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
6.3 mg-100 mg/5 mL oral liquid: 7.5 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
9 mg-200 mg: 2 capsules orally every 4 hours, not to exceed 6 capsules in a 24 hour period.
8 mg-200 mg/5 mL oral liquid: 5 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

12 years or older:
10 mg-100 mg/5 mL or 10 mg-200 mg/5 mL: 10 mL orally every 4 hours as needed, not to exceed 60 mL/day
10 mg-300 mg/5 mL: 5 mL orally every 4 hours as needed, not to exceed 40 mL/day
10 mg-300 mg, 10 mg-400 mg, or 20 mg-400 mg tablet: 1 tablet orally every 4 hours as needed, not to exceed 6 tablets/day.
7.5 mg-225 mg/5 mL oral liquid: 2.5 mL to 3.75 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
6.3 mg-100 mg/5 mL oral liquid: 15 mL orally every 4 to 6 hours, not to exceed 6 doses in 24 hours.
9 mg-200 mg: 2 capsules orally every 4 hours, not to exceed 12 capsules in a 24 hour period.
8 mg-200 mg/5 mL oral liquid: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Codeine-guaifenesin should be administered with plenty of fluids.

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