Alavert Disease Interactions
There is 1 disease interaction with Alavert (loratadine).
Loratadine (applies to Alavert) renal/liver disease
Moderate Potential Hazard, High plausibility. Applicable conditions: Renal Dysfunction
Loratadine is primarily converted by the liver to an active metabolite, and both parent drug and metabolite are excreted in the urine. Patients with renal and/or liver disease may be at greater risk for adverse effects from loratadine due to drug and metabolite accumulation. The manufacturer recommends one-half the regular dosage initially in patients with liver failure or decreased renal function (GFR < 30 mL/min). Due to the differential effects of hepatic impairment on the serum half-life and clearance of loratadine and pseudoephedrine, the use of products containing a fixed combination of these drugs is not recommended in the presence of liver failure.
Alavert drug interactions
There are 107 drug interactions with Alavert (loratadine).
Alavert alcohol/food interactions
There is 1 alcohol/food interaction with Alavert (loratadine).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
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