Disease Interactions

Alavert (loratadine) Disease Interactions

There is 1 disease interaction with Alavert (loratadine):

Loratadine (Includes Alavert) ⇔ Renal/Liver Disease

Moderate Potential Hazard, High plausibility

Applies to: Renal Dysfunction, Liver Disease

Loratadine is primarily converted by the liver to an active metabolite, and both parent drug and metabolite are excreted in the urine. Patients with renal and/or liver disease may be at greater risk for adverse effects from loratadine due to drug and metabolite accumulation. The manufacturer recommends one-half the regular dosage initially in patients with liver failure or decreased renal function (GFR < 30 mL/min). Due to the differential effects of hepatic impairment on the serum half-life and clearance of loratadine and pseudoephedrine, the use of products containing a fixed combination of these drugs is not recommended in the presence of liver failure.


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Alavert (loratadine) drug Interactions

There are 51 drug interactions with Alavert (loratadine)

Alavert (loratadine) food/lifestyle Interactions

There is 1 food/lifestyle interaction with Alavert (loratadine)

See also...



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