Insulin regular Disease Interactions
There are 2 disease interactions with insulin regular:
Insulin (Includes Insulin regular) ↔ Renal/Liver Disease
Moderate Potential Hazard, Moderate plausibility
Applies to: Renal Dysfunction, Liver Disease
Insulin requirements may be diminished in patients with renal or hepatic impairment due to reduced insulin metabolism and, in the latter case, also to reduced capacity for gluconeogenesis. Lower initial dosages may be appropriate, with careful monitoring of plasma glucose levels and dosing adjustments.
- "Product Information. Novolog (insulin aspart)" Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
- "Product Information. Lantus (insulin glargine)" Aventis Pharmaceuticals, Swiftwater, PA.
- "Product Information. Humulin BR (insulin)." Lilly, Eli and Company, Indianapolis, IN.
Insulin/Oral Hypoglycemic Agents (Includes Insulin regular) ↔ Hypoglycemia
Moderate Potential Hazard, High plausibility
Applies to: Adrenal Insufficiency, Autonomic Neuropathy, Panhypopituitarism, Malnourished, Anorexia/Feeding Problems
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
- "Product Information. Glucotrol (glipizide)." Pfizer US Pharmaceuticals, New York, NY.
- Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998):
- "Product Information. Glucophage (metformin)." Bristol-Myers Squibb, Princeton, NJ.
You should also know about...
insulin regular drug Interactions
There are 830 drug interactions with insulin regular
insulin regular alcohol/food Interactions
There is 1 alcohol/food interaction with insulin regular
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2016 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.