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Abecma Disease Interactions

There are 2 disease interactions with Abecma (idecabtagene vicleucel).

Major

Idecabtagene vicleucel (applies to Abecma) infection

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Idecabtagene vicleucel should not be administered to patients with active infection or inflammatory disorders. Signs and symptoms of infection should be monitored before and during treatment. Additionally, screening for cytomegalovirus infection (CMV), hepatitis B and C and HIV should be performed before treatment initiation. Viral reactivation of CMV and hepatitis has been reported, in some cases with fatal outcomes. Consider antiviral therapy to prevent viral reactivation.

References

  1. (2021) "Product Information. Abecma (idecabtagene vicleucel)." Celgene Corporation
Moderate

Idecabtagene vicleucel (applies to Abecma) renal/hepatic

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction, Liver Disease

Idecabtagene vicleucel has not been studied in patients with renal or hepatic impairment. Caution is advised.

References

  1. (2021) "Product Information. Abecma (idecabtagene vicleucel)." Celgene Corporation

Abecma drug interactions

There are 198 drug interactions with Abecma (idecabtagene vicleucel).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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