Skip to main content

Fruquintinib Disease Interactions

There are 5 disease interactions with fruquintinib.

Moderate

Fruquintinib (applies to fruquintinib) bleeding

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Bleeding Associated with Coagulation Defect

Fruquintinib increases the risk of hemorrhagic events which may lead to fatal outcomes. Closely monitor patients who are at risk for bleeding.

References

  1. (2023) "Product Information. Fruzaqla (fruquintinib)." Takeda Pharmaceuticals America
Moderate

Fruquintinib (applies to fruquintinib) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Fruquintinib has not been evaluated in patients with moderate hepatic impairment (total bilirubin greater than 1.5 times and less than 3 times ULN and any AST) and it is not recommended for treatment in patients with severe hepatic impairment (total bilirubin greater than 3 times ULN and any AST).

References

  1. (2023) "Product Information. Fruzaqla (fruquintinib)." Takeda Pharmaceuticals America
Moderate

Fruquintinib (applies to fruquintinib) hypertension

Moderate Potential Hazard, Moderate plausibility.

Hypertension was reported in patients taking fruquintinib. Fruquintinib should not be initiated in patients unless blood pressure is adequately controlled.

References

  1. (2023) "Product Information. Fruzaqla (fruquintinib)." Takeda Pharmaceuticals America
Moderate

Fruquintinib (applies to fruquintinib) infection

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Infection was reported in patients taking fruquintinib. Fruquintinib should not be initiated in patients with active infections. Closely monitor for infection during treatment and withhold treatment during active infection.

References

  1. (2023) "Product Information. Fruzaqla (fruquintinib)." Takeda Pharmaceuticals America
Moderate

Fruquintinib (applies to fruquintinib) thromboembolic events

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: History - Thrombotic/Thromboembolic Disorder

Fruquintinib may increase the risks for arterial thromboembolic events. Initiation of fruquintinib in patients with a recent history of thromboembolic events should be carefully considered.

References

  1. (2023) "Product Information. Fruzaqla (fruquintinib)." Takeda Pharmaceuticals America

Fruquintinib drug interactions

There are 213 drug interactions with fruquintinib.

Fruquintinib alcohol/food interactions

There is 1 alcohol/food interaction with fruquintinib.

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer