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Injectafer Disease Interactions

There are 3 disease interactions with Injectafer (ferric carboxymaltose).

Moderate

Ferric carboxymaltose (applies to Injectafer) hypertension

Moderate Potential Hazard, Moderate plausibility.

Transient elevation of blood pressure has been reported in clinical trials in patients receiving ferric carboxymaltose. These elevations generally occurred immediately after dosing and resolved in 30 minutes. Patients should be monitored for symptoms or signs of hypertension following treatment.

References

  1. "Product Information. Injectafer (ferric carboxymaltose)." American Regent Laboratories Inc (2013):
Moderate

Ferric carboxymaltose (applies to Injectafer) hypophosphatemia

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Malabsorption Syndrome

Patients with malabsorption of fat-soluble vitamins or phosphate, or using medications affection proximal renal tubular function, hyperparathyroidism, vitamin D deficiency, or malnutrition may experience symptomatic hypophosphatemia. Cases occur mostly after repeat exposure. Most cases resolved within 3 months. Monitor serum phosphate in at risk patiens requiring repeat treatment.

References

  1. "Product Information. Injectafer (ferric carboxymaltose)." American Regent Laboratories Inc (2013):
Moderate

Ferrous salts (applies to Injectafer) hypersensitivity reactions

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Allergies

Serious hypersensitivity reactions, including anaphylaxis- type reactions, some of which have been life-threatening have been reported in patients using some injection iron products. Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse. These products should be administered cautiously, especially in patients with a history of significant allergies. Patients should be monitored during and at least 30 minutes after the administration. Epinephrine should be immediately available in the event of acute hypersensitivity reactions.

References

  1. "Product Information. Feraheme (ferumoxytol)." Alza Pharmaceuticals (2009):
  2. "Product Information. Injectafer (ferric carboxymaltose)." American Regent Laboratories Inc (2013):

Injectafer drug interactions

There are 29 drug interactions with Injectafer (ferric carboxymaltose).

Injectafer alcohol/food interactions

There is 1 alcohol/food interaction with Injectafer (ferric carboxymaltose).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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