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Elvitegravir Disease Interactions

There are 2 disease interactions with elvitegravir.

Major

Elvitegravir (applies to elvitegravir) hepatic dysfunction

Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The use of elvitegravir is not recommended for use in patients with severe hepatic impairment (Child-Pugh Class C). No dosage adjustment is required in patients with mild (Child-Pugh Class A) or moderate (Child-Pugh Class B) hepatic impairment.

References

  1. (2014) "Product Information. Vitekta (elvitegravir)." Gilead Sciences
Major

Elvitegravir (applies to elvitegravir) renal dysfunction

Major Potential Hazard, Moderate plausibility.

The use of elvitegravir is not recommended in patients with severe renal impairment (estimated creatinine clearance below 30 mL per minute). No dosage adjustment is recommended in patients with estimated creatinine clearance greater than or equal to 30 mL per minute.

References

  1. (2014) "Product Information. Vitekta (elvitegravir)." Gilead Sciences

Elvitegravir drug interactions

There are 102 drug interactions with elvitegravir.

Elvitegravir alcohol/food interactions

There are 2 alcohol/food interactions with elvitegravir.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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