Generic Name: ciprofloxacin (Ophthalmic route)

sip-roe-FLOX-a-sin

Commonly used brand name(s)

In the U.S.

  • Ciloxan

Available Dosage Forms:

  • Solution
  • Ointment

Therapeutic Class: Antibiotic

Chemical Class: Fluoroquinolone

Uses For Ciloxan

Ophthalmic ciprofloxacin is used in the eye to treat bacterial infections of the eye (ophthalmic ointment and solution) and corneal ulcers of the eye (ophthalmic solution). Ophthalmic ciprofloxacin works by killing bacteria.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Ciprofloxacin ophthalmic preparation is available only with your doctor's prescription.

Before Using Ciloxan

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use is not recommended in infants and children up to 2 years of age (ophthalmic ointment) and 1 year of age (ophthalmic solution). In children older than 1 or 2 years of age, this medicine is not expected to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ophthalmic ciprofloxacin in the elderly with use in other age groups.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Agomelatine
  • Amifampridine
  • Cisapride
  • Dronedarone
  • Lomitapide
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Sparfloxacin
  • Thioridazine
  • Tizanidine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acarbose
  • Acecainide
  • Acetohexamide
  • Alfuzosin
  • Alosetron
  • Amiodarone
  • Amitriptyline
  • Amoxapine
  • Apomorphine
  • Arsenic Trioxide
  • Artemether
  • Asenapine
  • Astemizole
  • Azimilide
  • Azithromycin
  • Bendamustine
  • Benfluorex
  • Bosutinib
  • Bretylium
  • Chlorpromazine
  • Chlorpropamide
  • Citalopram
  • Clarithromycin
  • Clomipramine
  • Clozapine
  • Crizotinib
  • Cyclobenzaprine
  • Dabrafenib
  • Dasatinib
  • Delamanid
  • Desipramine
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Droperidol
  • Eltrombopag
  • Erythromycin
  • Escitalopram
  • Everolimus
  • Fentanyl
  • Fingolimod
  • Flecainide
  • Fluconazole
  • Fluoxetine
  • Gatifloxacin
  • Gemifloxacin
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Granisetron
  • Guar Gum
  • Halofantrine
  • Haloperidol
  • Hydrocodone
  • Ibrutinib
  • Ibutilide
  • Iloperidone
  • Imipramine
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Ivabradine
  • Ketoconazole
  • Lapatinib
  • Levofloxacin
  • Lopinavir
  • Lumefantrine
  • Lurasidone
  • Mefloquine
  • Metformin
  • Methadone
  • Mifepristone
  • Miglitol
  • Moricizine
  • Moxifloxacin
  • Nilotinib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Ondansetron
  • Paliperidone
  • Pazopanib
  • Perflutren Lipid Microsphere
  • Pomalidomide
  • Posaconazole
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinidine
  • Quinine
  • Ranolazine
  • Rasagiline
  • Salmeterol
  • Saquinavir
  • Sematilide
  • Sevoflurane
  • Simeprevir
  • Simvastatin
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sorafenib
  • Sotalol
  • Sunitinib
  • Tasimelteon
  • Tedisamil
  • Telavancin
  • Telithromycin
  • Terfenadine
  • Tetrabenazine
  • Theophylline
  • Tolazamide
  • Tolbutamide
  • Toremifene
  • Trazodone
  • Trifluoperazine
  • Trimipramine
  • Troglitazone
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Vilanterol
  • Vilazodone
  • Vinflunine
  • Voriconazole
  • Warfarin
  • Ziprasidone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Betamethasone
  • Chloroquine
  • Corticotropin
  • Cortisone
  • Cosyntropin
  • Cyclosporine
  • Deflazacort
  • Dexamethasone
  • Diclofenac
  • Dutasteride
  • Erlotinib
  • Fludrocortisone
  • Fluocortolone
  • Fosphenytoin
  • Hydrocortisone
  • Itraconazole
  • Methylprednisolone
  • Mycophenolate Mofetil
  • Olanzapine
  • Paramethasone
  • Phenytoin
  • Prednisolone
  • Prednisone
  • Probenecid
  • Rifapentine
  • Ropinirole
  • Ropivacaine
  • Sildenafil
  • Triamcinolone
  • Zolpidem

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Caffeine

Proper Use of Ciloxan

To use the ophthalmic ointment:

  • First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A ½-inch strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using the eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.

To use the ophthalmic solution (eye drops):

  • First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
  • If you think you did not get the drop of medicine into your eyes properly, use another drop.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

To help clear up your eye infection completely, keep using ophthalmic ciprofloxacin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For ophthalmic ointment dosage form:
    • For bacterial conjunctivitis:
      • Adults and children 2 years of age and older—Use a ½-inch strip of eye ointment in each eye three times a day for the first two days, then use a ½-inch strip of eye ointment in each eye two times a day for the next five days.
      • Infants and children up to 2 years of age—Use and dose must be determined by your doctor.
  • For ophthalmic solution dosage form:
    • For bacterial conjunctivitis:
      • Adults and children 1 year of age and older—Use 1 drop in each eye every two hours, while you are awake, for two days. Then use 1 drop in each eye every four hours, while you are awake, for the next five days. If you think you did not get the drop of medicine into your eyes properly, use another drop.
      • Infants and children up to 1 year of age—Use and dose must be determined by your doctor.
    • For corneal ulcers:
      • Adults and children 1 year of age and older—On day one, use 2 drops in the affected eye every fifteen minutes for six hours, then 2 drops every thirty minutes for the rest of the day, while you are awake. On day two, use 2 drops every hour, while you are awake. On days three through fourteen, use 2 drops every four hours, while you are awake.
      • Infants and children up to 1 year of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Ciloxan

If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.

This medicine may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.

Ciloxan Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare
  • Allergic reaction, such as skin rash, hives, or itching
  • blurred vision or other change in vision
  • eye pain
  • irritation (severe) or redness of eye
  • nausea

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning or other discomfort of eye
  • crusting or crystals in corner of eye
Less common
  • Bad taste following use in the eye
  • feeling of something in eye
  • itching of eye
  • redness of the lining of the eyelids
Rare
  • Dryness of eye
  • increased sensitivity of eyes to light
  • swelling of eyelid
  • tearing of eye

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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