Skip to main content

Sumatriptan for Migraine User Reviews (Page 3)

Brand names: Imitrex, Tosymra, Imitrex Statdose, Imitrex Nasal, Onzetra Xsail Zembrace SymTouch

Sumatriptan has an average rating of 7.5 out of 10 from a total of 438 reviews for the treatment of Migraine. 68% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Sumatriptan

  • Anonymous
  • October 15, 2009

Imitrex (sumatriptan) "Something that really works for me when my schedule allows is to take a short nap after taking Imitrex. I wake up with little discomfort. My head is clear. I can think. One of the worst symptoms of my migraines is that I cannot stay focused on a task. If I am unable to nap the Imitrex has little effect on me. This is horrible when you are at work as many of you know. "

8 / 10
Was this helpful?YesNo
28 Report
  • Anonymous
  • Taken for less than 1 month
  • November 24, 2023

"Took half the dose, felt fine for a while. Thankfully, didn't experience severe dizziness or tingling. But my arms started to feel very sore, like after an intense workout. And my throat felt hot in a weird way and made me feel kind of bleh all together. It did help the migraine a bit but didn't notice a big difference. I have severe anxiety and it is always better to be cautious of side effects before taking a new medicine, but your doctor prescribed it for a reason! It might help. In my experience, it wasn't awful but not the greatest either."

5 / 10
Was this helpful?YesNo
2 Report
  • Beefree
  • September 16, 2017

Imitrex (sumatriptan) "I am perimenopausal age 53 and for last several years suffered from debilitating migraines. I days wasted because I was too sick from these headaches. Forget Excedrin for migraines or any other OTC drugs no relief whatsoever. This past weekend I had a migraine that pretty much knocked me out - the pain was horrific, nausea, vomiting and cried like a baby. Finally went to emergency room and they gave me Imitrex. .. Within 30 minutes headache was gone. I was very sleepy but I don't know if that's a side effect or just from not sleeping the prior 3 days."

10 / 10
Was this helpful?YesNo
15 Report

Frequently asked questions

  • Erinl...
  • Taken for 5 to 10 years
  • September 7, 2017

Imitrex (sumatriptan) "Reading some of these reviews makes me wonder how much of a chance they gave the medication. I've had 'vascular' migraines since I was 13. I'm 35 today. I take Excedrin migraine for my headaches. I take Imitrex for my migraines. Used to be hard to tell the difference. I understand now the difference. But before I found Imitrex, I took all kinds of 'prevention' meds. Amitriptyline, nortriptyline, Zoloft, more than I can remember. Never prevented a darn thing. Just ended up with side effects from those. As a teen, that meant acne and weight gain. Aka, hell. It's been years now since I've found Imitrex. And like many, I was worried about trying it. But there came a day I couldn't NOT try it. 20 minutes later, I kicked myself for waiting."

10 / 10
Was this helpful?YesNo
15 Report
  • Minlet
  • July 7, 2017

Imitrex (sumatriptan) "I preferred Relpax, but my insurance stopped covering it. Imitrex works at least 95% of the time, but maybe 10% of those times, the headache recurs and I have to take another one (which almost never happened with Relpax). My side effects are weird but not debilitating: sense of pressure in head, neck, chest, shoulders, arms; tingling in face; dry burning eyes; skin sensitivity to hot/cold; taste sensitivity to spicy/sour; lack of appetite; sweat; thirst; diuretic. A bit sluggish and sometimes drowsy, but not truly fatigued. Almost never nauseous; never dizzy. A couple of hours later, I often feel mild muscle soreness. The side effects are stronger if I take it on an empty stomach, but it also works faster."

7 / 10
Was this helpful?YesNo
15 Report

Are you taking this medicine?

  • jaqpink
  • September 21, 2013

Imitrex (sumatriptan) "The only medication that works for my migraines, that last typically 3 days at a time, right side of my head, in my eye, down the back of my neck and upper back. I take the 100mg tablet, 1 every 12 hours, or when I feel it coming back on. Imitrex kicks in within 20 minutes of taking it. As close to instant relief as you can get. GREAT medication."

10 / 10
Was this helpful?YesNo
21 Report
  • heada...
  • November 3, 2014

Imitrex (sumatriptan) "Great. I've taken it twice and didn't experience any major side effects. Kicked in after 20-30 minutes, was fully ready to go at 60 minutes after. That said I did experience some side effects including: -mild heartburn-like feeling during the first 1-2 hours after taking it. -moderate heaviness/tightness in my jaw that lasted just about 12 hours after taking. -some drowsiness -some mild neck pain (which could have been the migraine) -a tightness/tingling (very mild) in my forearms. But I'm free and clear of the headache. Definitely plan on taking again"

9 / 10
Was this helpful?YesNo
19 Report
  • Kdhow
  • Taken for 1 to 6 months
  • June 20, 2018

Imitrex (sumatriptan) "I have had migraines (growing blind spots, with nausea and pain), and also tension migraines since childhood. Starting with my 3rd child, I started getting debiltating migraines. I’m talking, tingling fingers, trying to talk but my brain can’t find my words, PAIN that lasts at least 2 days with 1-2 of my brain not working. I tried Fioricet and it didn’t work. Magnesium aspartate supplements helped a ton with the tension and blindness headaches. Finally my dr gave me this and OH MY GOSH 30 mins later I felt so much better, by an hour it was gone!! I still feel like my brain is dulled for several hours but even though I can no longer feel the headache, it’s still there messing stuff up. On occasion I have to take two. If I let the pain get really bad before I take it, it takes longer to work. I can usually count on it being gone for 6-20 hours before I need to take again. I love it. Yes, neck stiffness, some jaw tightness... A MILLION AND TWELVE PERCENT better than a migraine though."

10 / 10
Was this helpful?YesNo
13 Report
  • MamaA...
  • Taken for 6 months to 1 year
  • December 21, 2016

Imitrex (sumatriptan) "I have suffered migraines maybe 4 times a year or so since I was little. Usually accompanied by vomiting and complete inability to function. The past two years, after having my second daughter, the migraines have amped up to 3 or 4 a month- sometimes more. Imitrex works almost always to eliminate the migraine. Every once in awhile I wait too long and have to take two. I have no side effects to speak of which is crazy to me because I can't even use herbal remedies without experiencing weird side effects. I'm thankful for the scientists who created this drug. I always have it with me just in case and it keeps me from being out for the count with my two little girls."

9 / 10
Was this helpful?YesNo
15 Report
  • Sleep...
  • Taken for less than 1 month
  • April 29, 2016

Imitrex (sumatriptan) "I was diagnosed with severe painful and silent migraines a few months ago, but the neurologist said I've most likely suffered from silent migraines my entire life (I'm 17 by the way), but recently they have started getting painful. Imitrex was the first medication I was put on. I was excited to start feeling better, but imitrex made me feel awful. I suffer from extreme nausea before, during and after a migraine and it's completely life ruining. I've tried imitrex many times, in hopes of it finally working. Every time I'd take it, I'd get a horrible burning in my throat, and my migraine would worsen. It didn't help nausea, aura, pain or any other migraine symptoms I suffer from. I've recently been put on another medication that'll hopefully work."

1 / 10
Was this helpful?YesNo
16 Report
  • dan
  • Taken for 5 to 10 years
  • November 28, 2019

Imitrex Statdose (sumatriptan) "this medication will take a migraine away in 20 minutes. If you have work that day or are trying to get to sleep this in invaluable to me once or twice a month. It stops the pounding quickly, especially accompanying a hot bath."

10 / 10
Was this helpful?YesNo
10 Report
  • Anonymous
  • Taken for less than 1 month
  • September 10, 2012

Imitrex (sumatriptan) "The first time I took this I got a severe panic attack. It felt like I couldn't breathe, my heart was racing and chest hurt. It did nothing for the pain or any of the other things associated with migraines. I did try it once more, as per my Dr, and it happened all over again. Maxalt is what I use now."

1 / 10
Was this helpful?YesNo
21 Report
  • Amc
  • November 16, 2013

Imitrex (sumatriptan) "Works super fast and well. Gets rid of my migraines fast when I take with a Motrin 800, BUT......it makes me sweat buckets. I took it at work before my shift and 2 hours later my migraine was gone but I had sweated through 2 shirts and was visibly dripping. It was pretty bad. It does it every time I take it so I try not to use it if I can help it."

7 / 10
Was this helpful?YesNo
19 Report
  • Nicky
  • Taken for less than 1 month
  • December 31, 2019

Imitrex Nasal (sumatriptan) "I LOVE this product ( the nasal imtrex) . I used to vomit terribly with the oral sumatriptan on top of getting very tired and also get rebound headaches. This works in about 9 mins and I get pain free sign no side effects!"

10 / 10
Was this helpful?YesNo
10 Report
  • kdp
  • Taken for less than 1 month
  • April 25, 2019

"It’s 3:19 in the morning. My wife just woke me up from a horrific gruesome nightmare I was having. Something horrific was happing in my dream and I was panicking in real life, when she woke me up I had tears coming out of my eyes. I heard this drug gives you nightmares but I didn’t think they would be like this. My head is still pounding and still have a migraine. I took this yesterday evening at around 5:30pm. After I took it I was throwing up for hours. It made me so sick. I’ll never take this again."

1 / 10
Was this helpful?YesNo
11 Report
  • Jen...
  • October 30, 2014

Sumavel DosePro (sumatriptan) "Best migraine medicine I have ever used. The injection does hurt for a few seconds but the pain is gone as fast as it came. Within a few minutes I can feel the medicine rushing through my head. It feels very heavy and leaves me with a dizzy sensation. I usually need about an hour of sleep and then the migraine is gone completely. I suffer about three migraines a week and only need a second dose about once a month. Pretty effective if you ask me! I have noticed that if I am feeling nauseous already, the medicine intensifies this. I found that taking a sublingual anti nausea medicine a few minutes before the injection greatly reduces this side effect."

10 / 10
Was this helpful?YesNo
18 Report
  • one...
  • December 22, 2015

Imitrex (sumatriptan) "I have been suffering from migraine's since around 16 and now at 36 although they have became less frequent over the years. They are horrible as I usually am out for the entire day bedridden in a dark room. I have always been very paranoid to try a actual migraine medicine so have taken vicodin for the pain. I recently had a migraine at work and decided to try a imitrex my doctor prescribed me. I was nervous to try it but am so happy I did. I waited a few minutes of having the migraine before I took it but it relieved me of my migraine within 30 minutes. I did experience some effects like muscle stiffness in my neck, tightness in my face and a burning feeling in my nose and forehead for about a hour but I'll take that any day over a migraine."

9 / 10
Was this helpful?YesNo
16 Report
  • Sumat...
  • Taken for 1 to 2 years
  • January 1, 2023

"Never had migraines until I quit drinking alcohol in my early '40s (daily drinker). Sumitriptan works really good on me. It says to take it immediately on the first onset but I hate taking meds so I wait 8 to 10 hours before I take it. In about an hour, I feel 100% normal with no side effects. I went to hormone Dr found out my testosterone was below the normal range. He prescribed a testosterone cream, DHEA & pregnenolone brought my test to the high end of the normal range. Within the first month, the frequency of migraines dropped from 4 or 5 per week to 2 per month. Now 6 months in & it's 1 migraine per month. Now my only triggers are dairy and a bad night of sleep. Before I would get triggered with almost anything. I also heard certain types of THC can get rid of a migraine. But the hormones seem to prevent them all together. The hormones also help me sleep better & can eat more foods."

10 / 10
Was this helpful?YesNo
4 Report
  • Elect...
  • Taken for 2 to 5 years
  • July 1, 2018

Imitrex (sumatriptan) "This drug will get rid of my migraine about 70% of the time, but I only use it when nothing else works because the side effects are almost as bad as the migraine itself. It makes my skin feel prickly and tight, and my throat feels tight and like I can't swallow. It gives me such intense nausea that I often don't speak when I take it because I feel like if I open my mouth, I'll throw up. From trial and error, the nausea seems to abate if I take it with food, but if I forget to take it with food I have to force myself to eat through the nausea. My brain also feels really foggy and basic actions are difficult when I take it. I'm glad there are people who don't react like this, but I am definitely asking to be switched to a different medication."

3 / 10
Was this helpful?YesNo
12 Report
  • dancin...
  • June 15, 2010

Sumavel DosePro (sumatriptan) "Had migraines since I was 13. Thirty years later and they are worse. Have tried Maxalt, Treximet, butalbital, Excedrin migraine, and Zomig, to name the ones I remember. Tried a sample of Sumavel DosePro this month. It is the only medication that stopped the pain 100%. Took 10 minutes to stop a bad migraine (8 on a 10 scale) and another 10 minutes to be back to functional. Was a bit disoriented and dizzy for that first 20 minutes. Relpax is my typical drug of choice nowadays but it doesn't stop the bad ones. It only stops the ones that I catch right away. But this Sumavel is my new knight in shining armor. I don't know how expensive it is yet but I'm headed back to the doctor this week to find out."

10 / 10
Was this helpful?YesNo
23 Report
  • Jenn
  • October 18, 2019

Imitrex (sumatriptan) "I almost always get migraines around my period or times of extreme stress. I was getting a migraine that began as nausea, hot flashes, dizziness and weakness the entire day. That night the pain started so I took 25 mg imitrex in 90 min the pain was gone. I felt some pressure where the pain had been and couldn’t lay on that side. A week later I feel another migraine come on and I wasn’t sure it was a migraine until the nausea came. Took imitrex again and the pain went away after 2 hours but then I got super drowsy and fell asleep and woke up an hour later shaky and anxious. I had not had a good nights sleep the day before so those symptoms may be attributed to lack of sleep but they went away after a few hours. I did try imitrex in the middle of a migraine with nausea, blurry vision, severe pain and it didn’t help. I was discouraged and did not take a second dose that time. I suggest taking imitrex as soon as you feel pain"

9 / 10
Was this helpful?YesNo
10 Report
  • Anony...
  • Taken for less than 1 month
  • December 11, 2018

"AWFUL. Taking the 50mg and 100mg gave me HORRIBLE side effects. I can say, my migraine went away, but to get to that point, I have to go through about an hour of uncontrollable crying, tightness in my chest and throat, VERY heavy, almost numb limbs, extreme body aches, nausea, cold sweats, and a pounding headache. Never taking it ever again."

1 / 10
Was this helpful?YesNo
11 Report
  • Anonymous
  • March 13, 2009

Imitrex (sumatriptan) "God bless Imitrex. I can take the injection either at the start of a migraine or right in the middle of it and it works like a charm each time. I don't know what I would do without it. My migraines were crippling but thanks to Imitrex, I have my life back."

10 / 10
Was this helpful?YesNo
24 Report
  • KAW
  • Taken for 10 years or more
  • June 30, 2022

Imitrex (sumatriptan) "Suffered terrible migraines since late teens. Started on Imitrex in 2000, over 22 years now and it is the only medication that has worked. Usually knocks migraine out within an hour, even when it is a severe one. I don’t know how I would cope without it. I’d be stuck in bed for two days before I discovered this miracle pill. I don’t have side effects from it either. It changed my life truly. I still get migraines constantly, usually in the mornings, but at least I can take a pill and get on with my day."

10 / 10
Was this helpful?YesNo
5 Report
  • Buzce...
  • November 25, 2016

"This med works well for me in about 30 mins. My comment involves the packaging. When you are struggling with a bad headache it is extremely stressful trying to open the plastic and foil the pill is sealed in. Don't always have scissors at handy. Any one else find this annoying ? Should be changed."

9 / 10
Was this helpful?YesNo
14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Migraine

Care guides

Symptoms and treatments

Medicine.com guides (external)