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Simvastatin User Reviews & Ratings (Page 3)

Brand names: Zocor, FloLipid

Simvastatin has an average rating of 4.8 out of 10 from a total of 131 reviews on Drugs.com. 32% of reviewers reported a positive experience, while 49% reported a negative experience.

Reviews for Simvastatin

  • happy...
  • June 18, 2015

For High Cholesterol "have taken Simvastin 80mg for eight years. Cholestrol level is down and stable. I wake up some nights around 3pm.wide awake.I get irritable and angry at times..high tummy pains.some days the need to urinate quite often.I didnt realise until reading information here that it may be the statins causing these side effects. All in all im happy with the results."

6 / 10
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28 Report
  • door
  • November 9, 2017

For High Cholesterol "Interesting reviews. Over the years I've been on one cholesterol drug or another. My numbers are down and acceptable to my GP. The latest is the generic simvastatin . Muscle soreness in legs, hips, wrists have seemed to be my life. Up every two hours to pee like clockwork, sometimes more irritable for no apparent reason and irregular heart beats I can feel, and are picked up by my BP machine. After reading these reviews, I'm going to self de-medicate for a spell to see if my sleep pattern changes as well as other possible side effects I've listed. It seems too many people have the same symptoms as me, and have stopped taking the medication with positive results."

5 / 10
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21 Report
  • Florida...
  • January 5, 2010

For High Cholesterol "Started taking Simvastatin 5 days ago. I warned my doctor that statin's caused cramping every time I took them. She assured me that would not be the case, she was wrong. Only 5 days and I've lost a nights sleep and am in pain most of the time."

1 / 10
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38 Report

Frequently asked questions

  • bigci...
  • Taken for 1 to 6 months
  • March 19, 2014

For Hyperlipoproteinemia "Simvastatin 40mg, one tablet taken at bedtime. I weighed about 240 lbs. This medicine is effective at lowering lipids and triglycerides when taken regularly. Clinical trials prove these medicines lower stroke & heart attack risk. Also take soluble fiber immediately after meals when possible to supplement cholesterol reduction and Vitamin B6 to lower homocysteine levels. Skip a dose if you are going to have alcohol beverages that evening or day, so it doesn't over-tax your liver. Same with acetaminophen. Most noticeable side effect is mild insomnia and some mild muscle stiffness, both managed with daily Yoga and regular exercise. Hoping to get lowering dose to 20mg in a month or so, assuming blood tests show positive results."

8 / 10
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29 Report
  • Taghe...
  • Taken for less than 1 month
  • September 21, 2012

For High Cholesterol "I am on 20mg. I take it right before I go to bed. After 15 minutes my heart starts racing. However, I have no problems falling asleep. If I had to take this in the morning I wouldn't be able to stand the racing heart. Other than that, I feel good so far. My cholesterol was 204 & triglycerides are at 130. I am 43 and have started walking 3 miles at a good pace 5-6 days a week. Drinking lots of water and no caffeine. I have just had my next blood work since being on this medicine, so we'll see if it's doing it's job."

5 / 10
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32 Report

Are you taking this medicine?

  • hondo
  • Taken for 10 years or more
  • December 5, 2018

For High Cholesterol "Took this drug for ten years. The past year I have been having trouble breathing and doing any physical exercise at all. Pharmacy ran out of the drug and after three days, all the trouble I was having went away. GP is going to change to another drug. Before taking any prescription, do some research on line and if you don't like what you read go to your GP and discuss."

1 / 10
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  • 480 C...
  • Taken for less than 1 month
  • August 14, 2017

For High Cholesterol "20mg x2 days... 1. Severe headache 2. No energy 3. Weekness 3. Very sleepy 6. Pain in ribs (L side more) I have discontinued the Statin and will change diet, take fish oil and low dose aspirin daily."

1 / 10
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21 Report

More FAQ

  • exman
  • November 23, 2017

For High Cholesterol "I have been taking ZOCOR for years and in that time I have developed a side effect which in talking to others on the same drug is quite common.....cold hands and feet. I started on 10 mg and presently take 40 mg. My cholesterol has been reduced but the discomfort associated with coldness at all times regardless of temperature and amount of clothing worn is very disconcerting. I have discussed this with several doctors and they all say its a side effect of ZOCOR. I cannot find this in the list of published side effects. I have also tried Liptor but the results were actually worse. What to do?"

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20 Report
  • maryk
  • August 18, 2011

For High Cholesterol "Had taken medication for 8 months noticed that my muscle control was weakening and had acid reflux , which I had to take medication for. After going off this medication my muscle control strengthened and acid reflux was gone. "

2 / 10
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33 Report
  • Lisa
  • Taken for 10 years or more
  • November 27, 2018

For Cardiovascular Risk Reduction "I have Coronary artery disease (CAD). Open-heart surgery in 2002. I have taken 20mg of Simvastatin for 16 years. The last 3 years, I have been in chronic pain. My torso, rib cage, upper back, under my arms on my rib cage, both shoulders. Deep sore muscle pain & stiffness in my back. I was diagnosed with Fibromyalgia. After a spine nerve test. Dr. said no Fibromyalgia but Myofascial. After trigger point shot. Dr. said no to that. Help!!!! The Doctors do not know why I am in pain. I have been depressed since 2014. Lately, I have insomnia nightmares and extremely tired when I wake up."

10 / 10
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17 Report
  • Barb
  • Taken for 10 years or more
  • March 13, 2019

For High Cholesterol "Have used simvastatin 40mg for years. Had been taking Teva generic without a problem. I was given Dr Reddy generic simvastatin on one occasion (due to lower price) and I developed flu-like symptoms (fatigue, body aches an general run down feeling) almost immediately. Since then, my doc has specified Teva brand, even though it costs more, since I've never had any issues with that. The generics are supposed to be the "same." However, the inactive ingredients and method of dispersal in blood stream can have differing effects on different people. Rhabdomyolisis runs in my family and I don't want to take any chances with other generic brands."

9 / 10
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  • Aunt...
  • Taken for less than 1 month
  • April 21, 2018

For High Cholesterol "I took one pill and about 12 hours later, I began to feel very tired. 18 hours later, I went to the grocery and didn't think I was going to make it back because I became so weak and short of breath. My legs felt so heavy - almost as if though I wasn't going to be able to to walk. At about 36 hours after the ONE pill, I experienced an explosive bathroom episode and saw very dark stool and several drops of blood in the toilet. It's now 48 hours later and just put a piece of spearmint gum in my mouth and cannot taste it or smell it. One pill did this!"

1 / 10
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18 Report
  • Babef...
  • Taken for 6 months to 1 year
  • February 4, 2021

For High Cholesterol "While taking statins and I tried many different brands. I experienced some of the worst side effects. I am a 72 year old retired registered nurse. I first started waking up in the middle of the night with horrible cramps in my legs, it felt as if a knife was sticking in my leg. Then I developed a rash under my breasts which after being prescribed 4 different creams just got worse. Then I got gout in my big toe and when I woke up in the morning my feet felt numb. The gout was so painful. I realize that I need statin because of my LDL and carotid artery blockage but when I stopped using the statin all these different symptoms went away."

1 / 10
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  • Barrry
  • October 8, 2011

For Cardiovascular Risk Reduction "58 yr old male. Heart attack 7 months ago, 98% blocked right coronary artery, stented. Been on Simvastatin and Plavix since I got my stent. Was on Lisinopril, but it caused hives. Not sure what is causing it but I have been freezing cold all summer, shivering cold. My legs ache almost constantly. Got blood work done this week, I will be seeing the Doctor in a few days and get the results. If I find that it was this medicine causing the chills I will discontinue it."

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29 Report
  • Lou
  • Taken for 1 to 2 years
  • February 28, 2021

For High Cholesterol "My bad cholesterol and good cholesterol were both low. My doctor put me on Simvastatin to bring up my good cholesterol. Over the course of a year the drug caused me debilitating leg and ankle and feet swelling. The whole time I never knew what was causing my swelling. I stopped taking the drug for 5 days and all the swelling went away very quickly. I’ll never take it again ."

1 / 10
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10 Report
  • Eilish...
  • Taken for less than 1 month
  • October 6, 2020

For High Cholesterol "Took three 10mg simvastatin tablets ... 1st night insomnia, 2nd night slept but nightmare and 3rd night slept but woke up feeling depressed and anxiety. Dr. said this wasn't from the simvastatin but I did so quit taking and it took 2 weeks to feel myself emotionally again. NEVER will I take a statin."

1 / 10
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  • tytulip
  • Taken for less than 1 month
  • April 6, 2018

For High Cholesterol "Feel like garbage! Actually called in sick to work one day cause of how bad I felt. Blah feeling, stuffy nose, constant hot flashes, weird dreams, don't sleep. Only been on for 3 weeks and I just can't take it. Will these symptoms pass? I'm 44, 5'6", 130 lbs - it's not weight - work out like a beast - but high cholesterol and heart disease run on my dad's side - recent #'s the bad LD keeps rising, at 200, overall # is 275 - Dr wants to try this but I just can't. Going to give supplements a try."

3 / 10
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  • Anonymous
  • December 9, 2009

For High Cholesterol "I began to have bruising around insulin injection sites; it looked like I was on anti-coagulants. I am having pain in my joints, and numbness and tingling throughout my body, including my face and tongue. I have a decrease in my ability to taste food. Also, I am bruising from mild injuries with dark purple areas at the site of the bruise."

2 / 10
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30 Report
  • Anonymous
  • December 30, 2010

For High Cholesterol "Took simvastatin only once and had a bad case of vertigo within 30 minutes of going to sleep. The next day I felt OK for the most part, but that night I was playing drums in my band and had to stop after 40 minutes (we normally practice an hour and a half or more) because I was so exhausted. The rest of the night I felt like my whole body was being squeezed, and my muscles were really weak. I woke up 3 times during the night with my heart racing and feeling like I was going to pass out. I drank 1 liter of water in 2 hours, and finally fell asleep at 4AM. If I hadn't improved after 4AM I would have gone to the hospital. The next day I felt almost 100%, but my left arm ached all day. And this was just taking it once. It's not for me."

1 / 10
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  • brsfan
  • Taken for 5 to 10 years
  • September 14, 2018

For Cardiovascular Risk Reduction "I am a 44 year old male who had a stent placed in my heart 5 years ago. I was on SIMVASTATIN and have numerous side effects such as; increased weight gain, extreme fatigue/tiredness, constipation, and stomach pain. Since I stopped taking SIMVASTATIN my side effects have disappeared. I have lost weight, my energy level has skyrocketed, no more constipation or stomach pain. I am exercising and on a diet, but these seem to be working more effectively without the medication."

1 / 10
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14 Report
  • Mona
  • Taken for 2 to 5 years
  • March 18, 2021

For High Cholesterol "I started on simvastatin 4 years ago. During that time I developed severe muscle pain and weakness. I also developed heart palpitations. Just recently I missed several doses and noticed all those issues were almost all gone. I have been pain free and feeling lots better. It is a good medicine but beware if you start having those issues cause it may be that medicine."

5 / 10
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9 Report
  • YYano
  • Taken for 10 years or more
  • November 8, 2018

For High Cholesterol "This lowers cholesterol just fine. Constantly forgetting things and can't commit many things to memory since starting the drug. I am not old - started at 40, and now 50 years old. For example, I've been typing all of my adult life and since taking the drug, I have to correct typos in every sentence since my fingers do not have their muscle memory either. Events my kids say I was present at, I have no recollection of at all."

2 / 10
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13 Report
  • Anonymous
  • December 20, 2010

For High Cholesterol "I've used this medication for many years. I'm currently at 60 MG per day (single dose). It has done a good job, although my good/bad ratio could be a bit better still. HOWEVER, I do notice muscle aches when I use it. If I stop it, they stop. They are generally not severe, and not bad enough for me to stop using it. I've been told (by my doctor and others) that an over the counter supplement called CoQ10 can help this-I've not tried this as of yet. For people with muscle issues(check with the doctor if severe, of course), it may be worth a try (the CoQ10, I mean)."

7 / 10
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25 Report
  • Anonymous
  • August 6, 2011

For High Cholesterol "I take simvastatin. My level was 238 and dropped to 200 on 1 x 10 mg per day but before the 238 I was 250. I am now on 20mg and soon to take blood work and no problem at all. I take at night. I am sure it will be lower. Also My husband had 243 and he is down to 138 on one 10 mg per day but he moves a lot and I'm not as much. I had NO SIDE EFFECTS and I am medicine sensative and was scared to take it but I am so glad I did so try a low dose then up it if you don't have any side effects. "

10 / 10
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24 Report
  • Billy...
  • April 29, 2009

For High Cholesterol "Original total cholesterol value was 237. Prescribed 10mm of Crestor and had stomach cramps. Two weeks later prescribed 10mg of Simvastatin. After 3 months, recent blood test revealed a total cholesterol value of 139. No side effects and all other blood test results were in normal levels. Works for me."

9 / 10
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25 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.