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Sertraline User Reviews & Ratings (Page 3)

Brand names: Zoloft

Sertraline has an average rating of 7.3 out of 10 from a total of 4,377 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Sertraline

  • Danie...
  • Taken for 1 to 6 months
  • January 16, 2020

Zoloft (sertraline) for Panic Disorder "Before taking this drug, I spent 2 weeks researching side effects as I was so nervous to take it. Let me just tell you that you will feel the side effects in the first 1-2 weeks (first week was awful) and I was only on 25mg. I kept reading reviews in hope that I just needed to stick it out. I AM SO THANKFUL that I did. I have been on 50mg for 3 weeks now, and every day feels better. I can talk to people, I feel calm, my heart doesn't race at 1,000 beats per minute anymore. I suffered from GAD, Panic disorder, depression, and social anxiety for years. It always impacted my relationships at home, at work, and I was finding it so hard to get through university. After years of never wanting to take ADs, I reached a point where I had suicidal ideations and ended up in the ED. Since then, I have not looked back, and I will keep taking this drug as long as I feel like this. THERE IS LIGHT AT THE END OF THE TUNNEL I PROMISE!! I had no hope. I thought I would feel this way forever. GOOD LUCK"

9 / 10
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  • Richard
  • Taken for 1 to 6 months
  • October 11, 2019

For Anxiety and Stress "I remember reading all the reviews on this site in hope and desperation of feeling better. My anxiety was through the roof. The main problem was not being able to sleep, waking up in sweats, and not being able to stay asleep through the night. The sleep deprivation was feeding my anxiety. I didn't know what was happening to me as I never had anything like this before. I am going to be honest in my review and let anyone know who is going to take Sertraline: the first few days were awful - I was getting suicidal thoughts and was very worried, but after the third day it subsided along with any other side effects. I did appreciate my appetite being suppressed as I did need to lose some weight. If you stick with it after 2-3 weeks, my anxiety eased and now I am two months in, I feel about 99% me. I would also suggest having therapy as this helped me and have someone with you those first days when it can get bad. To anyone who is suffering at the moment, please give this a try. Very best wishes."

10 / 10
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  • brossi
  • June 9, 2010

Zoloft (sertraline) for Depression "Without Zoloft, I would probably be dead or killed. I have been taking Zoloft for 19 years. Since my daughter was born, the doctors have tried to take me off, but the depression started again. I did counseling and reduced the dose, but to be completely off makes me mean. I snap at people, easily irritated, road rage, body feels like it will explode with anxiety. It has never affected my sex drive. No weight gain can be blamed on Zoloft, probably feeling more sociable and going out to eat has caused a little weight gain. No headaches. Thanks for reading and I hope I helped."

9 / 10
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Frequently asked questions

  • KGrrrrl
  • Taken for 1 to 6 months
  • October 5, 2018

Zoloft (sertraline) for Depression "I suffer from SAD, or seasonal affective disorder, depression, and anxiety. All of my symptoms have increased as I've gotten older. Last year I took Lexapro, which was too numbing, affected my executive function, focus, short-term memory, and libido in a bad way. This fall, I decided to be proactive and got on 50 mg of Zoloft. Completely life-changing experience! Side effects were nothing compared to Lexapro. Maybe 1 or 2 days of mild nausea, slight insomnia for the first 2 nights. Now, at 5 weeks, I feel clear, happy, functional, and optimistic. Libido intact. Takes a bit longer to orgasm, but it's kind of amazing because it prolongs the intensity. Zoloft has truly changed my life for the better, hopefully it will continue to work; will take it forever if possible! Wanted to leave this positive review because there are so many negative ones out there, which don't paint an accurate picture of any drug. Negative experiences are always reported more than positive ones. :)"

10 / 10
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  • Anne
  • January 18, 2009

Zoloft (sertraline) for Depression "I am 55 years old and have been taking Zoloft for over 20 years. For me, it has been a miracle medicine. I find I am much more on an even keel, and while some things still upset me, it's far less than without Zoloft. I find, too, I am much more rational in my thought processes and am more confident in the choices I make. I have several medical conditions that contribute to feeling depressed, overwhelmed, and yes, even suicidal, but since I began my therapy with Zoloft, I want to live. Without Zoloft, I did not. I encourage anyone who feels depressed to seek help by finding the right medication for you. Life is hard enough without having to cope with feelings of severe negative emotions. I am so grateful for whoever created Zoloft."

10 / 10
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Are you taking this medicine?

  • Mich
  • Taken for 1 to 6 months
  • February 10, 2020

Zoloft (sertraline) for Depression "This drug saved my life. I started having chronic anxiety and depression very suddenly, and insomnia. I am so thankful for the positive and encouraging reviews on websites like this, because they helped me push through this difficult time, and I hope to do the same for someone else. I agree with many other reviews that it does get worse before it gets better. My anxiety increased at first, I think out of desperation for each day to finally be the day I would feel normal again. But it takes time and patience, and there will be ups and downs. I started seeing improvement around 4 weeks, but took a dive again around week 5 before increasing my dosage. Now I am at about week 7-8 and I would say 90% myself again. I highly recommend doing therapy too, and Xanax has helped curb the increased anxiety while my body adapts. Side effects are minimal, just nausea if I don’t take it with food. Zoloft helped me get my mind back under control and enjoy life again!"

10 / 10
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  • LS2020
  • October 12, 2020

Zoloft (sertraline) for Postpartum Depression "My baby is 9 weeks old today. I have been on zoloft for the past month. I promised myself that if this drug helped me I would come on here & give a review. Just after my 3rd child was born I hit absolute rock bottom. I cried at least 30 times per day. I couldn’t face going into the nursery or making dinner. I felt short tempered & despair. My doctor gave me zoloft. I started on half a tab at night (now 1 tab). The first 3 nights I was ill. I was rocking with anxiety. I was gasping for breath & I swore black & blue that I was not going to continue with the tablet. Then the morning would come & I felt a bit better. I have not cried once since. I am strong in the mind. I can enjoy my kids. I can put make up on, do my hair, do groceries, bath all kids, dinner. I am me again. I do not feel lowly. Do I feel elated & like I am living on cloud nine? No. I feel strong. I feel capable & calm. I wish you all the best in recovering from & seeing the good side to life again."

10 / 10
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More FAQ

  • Snakeye
  • Taken for less than 1 month
  • September 24, 2020

Zoloft (sertraline) for Major Depressive Disorder "Greetings! I have been on 13 antidepressants in the last ten years for my MDD and GAD. Some worked better than others, but most pooped out after a relatively short time. Others gave me dreadful side-effects like akathisia. I am seeing my third psychiatrist and he has suggested Zoloft. I have very little hope of it working. I begin my regiment on Friday so that I have the weekend as a slight buffer before work on Monday. Positive thoughts and prayers are appreciated. I will follow up this "review" in a few months whether successful or not. I am a married father of four and I just want to be a better husband to my wife and a better father to my children. Most of my friends and colleagues would be surprised if they knew the depth of my mental illness. I hope that all that are reading this find peace and healing."

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  • Muchb...
  • Taken for 1 to 2 years
  • December 29, 2013

Zoloft (sertraline) for Obsessive Compulsive Disorder "I have now been on Zoloft for a solid 12 months (50mg). It has changed my life. I was prescribed it for depression, anxiety, and Post-Traumatic Stress Disorder - it has almost completely resolved issues I have had for most of my life. I hesitated in taking it due to side effects, mostly because I have always been obsessed with my weight. I'm happy to report that if anything, I have dropped weight in the last year. I no longer am tempted to binge eat and just lead a healthy and active lifestyle because I am happier. I really wanted someone to read this who was in my position - who was too scared to try it because of side effects. My only side effects are dry eyes, I need to sleep 8 hours a night (instead of 5-6) and that's the worst of it!"

10 / 10
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  • Hannah
  • Taken for 6 months to 1 year
  • November 10, 2023

For Anxiety and Stress "This time last year I was reading reviews on here wondering whether I should start sertraline or not. I had previously had an awful experience with citalopram, so I was scared of taking another SSRI. The reviews really put me off. People tend to voice only a negative experience rather than a positive one, and I promised I would write a review if I had a positive one with sertraline, so here we go! Sertraline has absolutely changed my life. This time last year, I couldn't leave the house. I felt constant dread, my stomach was always upset, I couldn't sleep, and I would cry all the time. After being on this medication for 11 months, I am now in university, in a relationship, see my friends, don't cry over everything (I can still cry), I don't have any issues with orgasms, and my sex drive has actually increased! I can just nip to the shop like it's no biggie! I'm loving life again!"

10 / 10
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  • Stone
  • Taken for 1 to 6 months
  • June 7, 2020

Zoloft (sertraline) for Depression "I’m 50 and have struggled with anxiety because of my 26 year relationship with my wife. After 60 days I don’t have the breakdowns any more and can function. Zoloft helped me to close off to her and begin to feel safe emotionally. It really works."

9 / 10
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  • Jessie
  • Taken for less than 1 month
  • March 30, 2021

For Anxiety and Stress "Hi I have been been battling anxiety for about 6 years. I suffer with really bad intrusive thoughts. I’ve taken Zoloft (sertraline ) in the past and it really works I started to feel the normal me again no intrusive thoughts anymore. I decided to stop taking it and what happen 1 year later and 3 months my anxiety came back and my thoughts too. So I am back on Zoloft. I am on 50mg. I’ve been taking it for 1 week and half already I am again experiencing side effects like anxiety spiking, sweating, insomnia and upset stomach but it only last for a couple of days. I have experienced the side effects before when I first took Zoloft.. I just hope this review helps people that are going through the same situation that I am going through. What I do recommend is to stick with the Zoloft the fist days it feels like a nightmare but then one day you will wake up and no more anxiety and intrusive thoughts..:)"

10 / 10
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  • Zubzub
  • Taken for 2 to 5 years
  • May 31, 2020

For Anxiety and Stress "What can I say... I was initially on sertraline for 3 years, and I felt the best I’d felt in a long time, so I decided to slowly come off. I came off them, and depression hit me hard last week, so I was restarted on them. My depression and anxiety are horrifically worse than before I started the medications, but past experiences and the reviews on here remind me that the first 2 weeks are horrific, then things pick up. Long-term, these are fabulous & I cannot wait till I’m back to that feeling because my days at the moment are a constant struggle of tears and anxiety. But I know, I will get there."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • September 3, 2020

Zoloft (sertraline) for Panic Disorder "Around a month and a half ago I had hit a VERY LOW point in my life after a panic attack. I knew there was something wrong. I couldn’t sleep, I was CONSTANTLY worrying, and I felt very empty. I had bad tremors, I felt numb, and could not stop crying. I developed general anxiety disorder. It put me in a deep spiral. After being prescribed klonopin to help me sleep, I knew I had to try out a medication. My doctor put me in Zoloft 25mg, and a week later bumped me to 50mg. Zoloft literally saved my life. I never thought I could begin to feel myself again, no worrying, not anxious to do things, and very much more present. I will say it gets much worse before it gets better. Stick it out. Literally changed my life."

10 / 10
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  • Suz
  • Taken for 1 to 6 months
  • October 18, 2023

For Anxiety and Stress "For anyone struggling with the first few days/weeks/months, please stick with Sertraline. I was where you are now and I used to read all the reviews and pray that it worked for me. It did! I was no longer having racing heart, negative thoughts, and an absolutely crushing feeling of anxiety in my stomach every morning when I woke up, it just all went away! At the beginning, I couldn't even get out of bed, and now I am back at work, enjoying my family, my beautiful grandchildren. I started on 50mg and now take 100mg daily. Please stick with it, and I hope it works for you!"

10 / 10
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  • you...
  • July 22, 2021

Zoloft (sertraline) for Obsessive Compulsive Disorder "I have OCD, and honestly, this medication has given me my life back. This was the second med I took; lexapro was horrible for me. I have been taking Zoloft for 3.5 months. I was also seeing an OCD therapist through NOCD. You will definitely see better, faster results if you use this medication in conjunction with therapy. I first did have some negative side effects: GI upset, increased moodiness, fatigue, etc. this lasted for 8 days, and with dosage increases I also felt wonky for a few days. I also LOST weight, which was an added bonus. :)Please know this med is not a magic pill, it does take time to work which can be terribly frustrating at first. But WOW, I cannot tell you what I different place I am in. I just feel like myself again. I do still have intrusive thoughts, but I am ruminating much less and I no longer give these thoughts attention. My anxiety is significantly less and I am just so much happier. God bless everyone, I know OCD can be tormenting but you have GOT THIS!!!"

10 / 10
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  • Ciaran
  • Taken for 1 to 6 months
  • April 1, 2024

For Generalized Anxiety Disorder "Sertraline literally did everything I wanted it to do. In December 2023, I went through a severe bout of anxiety for no apparent reason. It may have been after a stint of the flu I had. My mind went into overdrive, and I was in a panic for literally 6 weeks. When I started sertraline 50mg, I was so, so, so skeptical. Granted, the first 2 weeks were hardcore difficult with side effects (didn’t take benzos as I wanted to fight through myself). Fast forward to 3 months in, and I feel absolutely incredible! Incredible meaning, I am back to my good old self - anxiety went from 10/10 to literally 0/10. I haven’t had intrusive thoughts or any, I mean any, anxiety symptoms since week 6. Will I stay on it long term? Who knows... I will do a year on it as it has changed my life for the better without a doubt. If anyone is going through the wringer, give it a try. It has brought me back from the brink, and I couldn’t be more delighted with life! :D"

10 / 10
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  • Matt
  • Taken for 1 to 6 months
  • March 14, 2024

For Anxiety and Stress "I wanted to take the time to write a review, as reading all those already on this site got me through the first 6 weeks of taking sertraline. I experienced every side effect possible and felt so low I ended up in hospital after a few days of taking them. However, I'm now on week 8, and my life is transformed. My anxiety/depression has pretty much gone, and I can go about my life as normal. My advice - STICK WITH IT, it does get better. Reach out and use the support of your friends and family if you struggle initially."

10 / 10
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  • Things...
  • January 3, 2021

Zoloft (sertraline) for Obsessive Compulsive Disorder "I had a random thought one day that has felt like it destroyed my life. I had the worst thoughts imaginable and it had gotten so bad to where I had to take a leave of absence at work and could not stop crying. I had thought about committing myself because I felt like I was losing my mind. I started working with an OCD therapist that confirmed I had Pure O. It helped me by doing ERP and ACT that I was able to go back to work and manage to live life. I was still struggling everyday and meditation was my only way to calm myself. I'm on Zoloft 25mg now. I have had no side effects. I noticed being able to see my thoughts clearly and distinguish what’s real and what’s in my head now. I am enjoying life and feeling more happy in every aspect. I still get thoughts but they don’t bother me since I don’t feel the need to ruminate or find out what’s “true” anymore. I plan to stay on this low dose as just enough to help me while I continue to do the work."

9 / 10
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  • Andrea
  • March 1, 2019

Zoloft (sertraline) for Premenstrual Dysphoric Disorder "I used to cry uncontrollably, be extremely irritable, uncomfortable in my body, lethargic, so depressed I couldn't get out of bed, have suicidal ideation, etc. Now with Zoloft, I have NONE of those symptoms anymore. My relationships are no longer being torn apart. I don't feel embarrassed by illogical mood swings or uncontrollable blabbering. I don't cry myself to sleep. I feel happy, optimistic, peaceful, and completely BALANCED. Zoloft has given me my life back. I had to stop taking it for 2 months due to a different health issue. ALL of my symptoms returned. I was basically losing my mind for two months. A couple of weeks back on Zoloft and I was again calm, happy, peaceful. I don't have any noticeable side effects. I started at 25mg for the first 5 months (still got quite lethargic and depressed) and now I am on 50mg, and I'm like all those women running through fields in white dresses in tampon commercials. Who knew, it isn't the tampons making them so happy...it's the Zoloft!"

10 / 10
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  • Carson
  • Taken for 5 to 10 years
  • June 12, 2021

Zoloft (sertraline) for Panic Disorder "I started having panic attacks/ anxiety since I was 16 years old. Things got real bad in my late 30’s early 40’s. I would drink alcohol at night to self medicate. I tried therapy and my doctor would always try to put me on an a anti depressant. I was too scared ,thinking it would make it worse! After having a nervous breakdown and being hospitalized 6 years ago they put me on Zoloft 50gm and Lamictal 25gm and I finally have my life back!!! It was like a light switch finally came on in my head! So much more calm, not worrying all the time, not wanting alcohol to cope. I haven’t had a drink in 6 years! It has truly has been a life saver for me and I give God all the glory. Sides effects were minimal, 1st week - insomnia and night sweats after that, completely fine! I wish all of you the best of luck and it will get better! Trust me, I thought I was hopeless!"

10 / 10
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  • lisalee
  • February 3, 2021

For Generalized Anxiety Disorder "I was so worried about side affect as my anxiety is based around health anxiety. I have been on them 12 weeks so here is my side effects I had a week of needing a number two and needing to go immediately it was very loose. I had extreme tiredness which last 2 week and for the first 2 week I didn't have much of an appetite and I had night sweats which lasted the longest of all the side effects. At 5 week the only side effect I have is I find it takes me longer to climax. I sweat more that I used to. I have had 3 times were I have talk my self down from a panic attack - which is great considering before I was having a panic attack a day and I couldn't even talk myself down from one. Week 5 was my turning point felt amazing the things I worried about seemed a distant memory and I could function properly with out this worry on my sholders or working my self up resulting in a panic attack. Please be kind to your self I wish you all the best in your journey to better mental health"

10 / 10
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  • Edman
  • Taken for 1 to 6 months
  • February 24, 2020

Zoloft (sertraline) for Social Anxiety Disorder "I was in a really bad place. I have had social anxiety most of my life due to trauma in my early life. After experimenting with LSD and having children my symptoms worsened dramatically. I started therapy and after a year I wasn't getting any better. My Dr suggested Zoloft because along with anxiety I had a lot of symptoms of PTSD. I felt it right away. I started at 25mg then up to 50mg and now I am at 100mg. I am a person that couldn't make phone calls , wouldn't leave the house alone, and I am at 0% anxiety. My mind is clear for the first time in years. Someone else used to term fearless and said they could tell people things they never would before. I kind feel that way as well. I had side effects each time I raised the dose but they went away after about 2 weeks each time. It was a little rough at first but I hung in and the last few months have been some of the best of my life."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • June 9, 2020

For Depression "Back in February I started having hot flushes, then felt dizzy and odd day a bit down, then a week later I had anxiety, which I had the same in 2007 when my mum died, so my doctor put my on sertraline, I went from a dose 25mg to 50mg and true for the first two months I had every side effect, head aches, blurred vision, cloudy brain, sick, anxiety, up and down days but came on this group to keep my positive and kept with them, now 5 months on I'm almost back to myself I do have odd days but that's life, and just get over it, so for anyone just starting sertraline, please be ready for a few weeks of feeling really rubbish but believe me u will soon start to feel better and it will work for u so hang in there, As we all deserve to be happy."

10 / 10
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  • megabs
  • Taken for 1 to 6 months
  • January 10, 2021

For Generalized Anxiety Disorder "I suffer from anxiety and derealisation. This medication is a life saver. I rated it a 9 because the side effects are horrific. If you are just starting off please give it time. It took me 8 weeks to start to feel normal again. I would read all the reviews trying to find an answer but instead I put myself down reading the negative ones. Be patient and be kind to yourself, it is hard and you do feel like its never going to get better. I promise it will, hang in there. I was in such dark place but there is light at the end of the tunnel. Don't expect to feel better overnight it is such a gradual thing and it will take time but you will get there!! One thing I would say is don't bottle it up, if you are having a bad day, speak to someone don't let it feel like you are going backwards because everyone has bad days."

9 / 10
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200 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.